Inside Matters

For years, the spotlight in microbiome research has been firmly on the gut. We’ve learned that diversity there is generally a good thing—linked to resilience, health, and better outcomes.

But what if one of the most important microbiomes in the body follows completely different rules?

In a recent conversation, Dr James McIlroy sat down with Professor David MacIntyre, Director of the Robinson Research Institute, to explo...

Dr Debra Silberg joins Inside Matters for a deep, wide-ranging conversation on gut health, drug development, and the future of microbiome therapeutics.

Dr Silberg is the Chief Scientific Officer at Beyond Celiac, a former global clinical leader at Shire/Takeda and AstraZeneca, and one of the most respected figures in GI medicine and microbiome science.

In this episode, we explore: • How she moved from basic science to medicine to p...

In this episode, Dr James McIlroy chats with Dr Tanya Mongan, clinical associate professor and gastroenterology consultant at the University of Nottingham. Dr Mongan specialises in gut health, particularly the gut–brain connection and faecal microbiota transplantation (FMT).

She talks us through the current state of FMT, why it works so well, and how it’s becoming an increasingly important treatment for conditions ...

Revolutionising Liver Health: The Link Between Gut Health, Genetics, and Lifestyle

In this episode, we dive deep into the intricate connections between liver health, gut health, genetic predispositions, and lifestyle factors. Our guest, Gary, a seasoned physician and entrepreneur, shares his extensive experience from pioneering liver disease research in the 90s to running a successful metabolic clinic focused on functional medicine...

In this episode, Dr. James McIlroy interviews Dr. Ran Blekhman, an associate professor at the University of Chicago, about the microbiome and its role as 'our second genome.'

Dr. Blekhman shares his research findings on the genetic and environmental factors that shape the microbiome, the heritability of microbial genes, and the relationship between the human genome and microbiome. They also discuss Dr. Blekhman's groundbreaking res...

In this episode of Inside Matters, I'm joined by Dr Johan van Hylckama Vlieg, Chief Scientific Officer at Freya Biosciences. As a global leader in microbiome research, Freya is pioneering innovative approaches to women’s health through biotherapeutics that are rooted in groundbreaking microbiome science.

00:00 Introduction to Dr. Johan van Hylckama Vlieg and Freya Biosciences 01:39 The Potential of the Microbiome 03:08 Challe...

The Gut-Health Revolution | Dr Chris Damman on Nutrition, Microbiome & the Future of Wellness

Dr Chris Damman brings decades of experience from the biotech world and leading global foundations to share his vision for the future of health and nutrition. In this episode, we dive deep into the transformative power of gut health and the emerging science shaping how we eat and live.

Gut Health: Ancient Wisdom Meets Modern Science Dr...

In this episode of Inside Matters, Dr James McIlroy is joined by Professor Yan Yiannakou to discuss the developments in IBS treatment.

Irritable bowel syndrome (IBS) is often brushed off as little more than an inconvenience. But in a recent conversation between Dr James McIlroy and Professor Yan Yiannakou, a consultant gastroenterologist with decades of experience, it’s clear that IBS is far more serious than many realise. Th...

In this episode of Inside Matters, Dr. James McIlroy sits down with Cory Greenberg, a professional cyclist and founder of Ride4IBD.

Cory shares his inspiring journey from his initial diagnosis of inflammatory bowel disease (IBD) while training as a professional cyclist, to overcoming the challenges posed by the disease. The conversation covers his approach to gut health in the context of athletic performance, insights into training...

In a fascinating conversation with Professor Max Nieuwdorp of the Amsterdam Medical Centre, Dr James McIlroy explores groundbreaking ideas and research surrounding the microbiome, hormones, and their profound impact on metabolic diseases. This insightful dialogue uncovers the remarkable potential of faecal microbiota transplant (FMT) and emerging pharmaceutical strategies in tackling obesity, diabetes, and even cancer.

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Exploring the Human Microbiome with Dr. Joël Doré: The Future of Gut Health Science

In this episode of Inside Matters, Dr James McIlroy engages in an enlightening conversation with Dr. Joël Doré, Research Director at the French National Research Institute for Agriculture, Food and Environment (NRAE). With over 40 years of experience in microbiome research, Dr. Doré shares his extensive knowledge on probiotics, gut health protocols,...

In a conversation with Dr. James Kinross, a senior lecturer and consultant surgeon at Imperial College London, various aspects of the human microbiome are explored. He is also the author of "Dark Matter: The New Science of the Microbiome".

Dr. Kinross discusses what constitutes a healthy microbiome and the challenges in analyzing it. The conversation also covers new research linking microbiomes to the effectiveness of cancer drugs,...

In this episode of Inside Matters, Dr. James McIlroy is joined by Professor Anthony Hobson, founder and CEO of the Functional Gut Clinic.

They discuss gut health diagnostics and treatments, focusing on the evolution of gut health understanding and therapies. Key topics include microbiome diagnostic testing, the importance of understanding gut functions, the impact of lifestyle on gut health, and the effi...

In this conversation, Dr James McIlroy and Emma Storey-Gordon discuss common myths and misconceptions surrounding health, fitness, and nutrition.

They explore the law of diminishing returns in exercise, the latest science in nutrition including fasting and protein consumption, and the importance of meal timing and insulin sensitivity.

Emma shares practical advice on setting nutrition targets, the gradual increase of fibre intake fo...

The following is a conversation with Dr. Momo Vuyisich, co-founder and chief scientific officer at Viome. Viome is a life sciences company that analyses the activities in your oral microbiome, gut microbiome, and blood using RNA, essentially measuring gene expression.

This gives the company the ability to be able to assess what the microbiome in these various areas of the body is doing and gives insights into potentially how that l...

The following is a conversation with Professor Jack Gilbert, a professor at the University of California, San Diego, along with his many other very interesting titles and job roles. This includes the co-founder of the Earth Microbiome Project, the American Gut Project, and also featured in the very popular recent Netflix documentary, Hack Your Health.

He is a master of the microbiome. We covered all aspects of the microbiome, the o...

Learn more about this episode's guest and the topics discussed - https://insidematters.health/

In this conversation, Dr James McIlroy and Mads Friis discuss the fundamentals of health and wellness. They cover topics such as mindset, sleep, diet, alcohol, and the importance of social relationships.

Mads emphasizes the importance of eating real food, including fruits, vegetables, and berries. He also highlights the significance of ge...

The following is a conversation with Dr. Jenna Macciochi, an immunologist, twice-published author, TEDx speaker, public speaker, and all-around immune system expert. 

It was an absolute pleasure and honour to have her in the studio today to talk about all things immune system. gut health, the microbiome, and even things like how do we improve the health of society more generally. Jenna truly is an expert. She's amazing at comm...

The following is a conversation with Dr Saman Maleki, associate professor at Western University with a special focus on oncology, immuno oncology, microbiology, and everything to do with the immune system and the microbiome.

Dr Maleki is a pioneer and a world leader in the field of sensitising tumours to immunotherapy through modulating the microbiome.

During this conve...