Science@UH

Science@UH

The University Hospitals Research & Education Institute Science@UH podcast illuminates the latest research discovery, innovation and clinical advances that helps accelerate new ways to treat and care for patients and improve the lives within our community and beyond.

Episodes

June 18, 2026 28 mins

Explore the rapidly evolving world of CAR T-cell therapy and how scientists are reengineering the immune system to fight disease. Drs. David Wald and Reshmi Parameswaran discuss breakthroughs in cancer immunotherapy, including faster manufacturing, next‑generation CAR T-cell design, and efforts to expand these therapies from blood cancers to solid tumors and autoimmune diseases. This conversation highlights the promise&nb...

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The pace of change in cardiometabolic medicine is accelerating. Ian Neeland, MD, breaks down the latest innovations in incretin therapies, from oral medications to cutting-edge combinations, and what they mean for weight loss, heart health, and long-term patient care.

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Matthew Anderson, MD, PhD, and Tyler Miller, MD, PhD, discuss how immune biology is reshaping neuroscience - from autism and obesity to CAR T cell therapies for glioblastoma and the challenge of crossing the blood brain barrier.

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Jennifer Villwock, MD, explains the neurocircuitry of smell, her rapid essential-oil–based AROMA test, and how olfactory dysfunction can inform clinical care and research spanning sinonasal disease, post-viral loss, and cognitive health.

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Molly McVoy, MD, dives into the mental health crisis affecting teens, why anxiety and depression have risen dramatically, and shares breakthrough research using EEG biomarkers and self-management programs that help teens build resilience.

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Theodoros Teknos, MD, and Gary Schwartz, MD, discuss how the recent $25.5 million NCI grant renewal solidifies Case Comprehensive Cancer Center as a powerhouse consortium delivering cutting-edge clinical trials, early detection and community-focused cancer prevention across Northeast Ohio.

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Join Dr. Daniel Simon as he interviews Dr. Igho Ofotokun, Chair of the Department of Medicine at University Hospitals. Dr. Ofotokun shares his remarkable journey from Nigeria to becoming an expert in HIV research, revealing how passion and experiences shaped his career in infectious diseases. Discover the pivotal moments that guided him in the fight against not just HIV, but also the challenges posed by COVID-19.

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Stanley Bazarek, MD, and Jennifer Sweet, MD, discuss the latest advances in neuromodulation, peripheral nerve surgery, and neuroengineering, highlighting the critical role of multidisciplinary collaboration between UH, Case Western Reserve University, and national research partners in translating these innovations from the lab to patient care.

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Varun Sundaram, MD, PhD, discusses how his experiences shaped his groundbreaking work in global heart failure research, from uncovering international differences in patient care to leading studies on GLP-1 therapies and advanced heart failure.

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Neuropsychiatrist Brian Appleby, MD, discusses prion diseases, including Creutzfeldt-Jakob disease, and the groundbreaking research and clinical trials at University Hospitals aimed at better understanding these rare but fatal neurodegenerative conditions.

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Amanda Amin, MD, Janice Lyons, MD and Alberto Montero, MD, explore the evolution of breast cancer treatment. The discussion highlights how personalized care, clinical innovation and compassionate teamwork are transforming patient outcomes.

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Guilherme Attizzani, MD, shares his inspiring journey beginning as a research fellow in intravascular imaging and rising to become a national and international leader in structural heart disease interventions.

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Aasef Shaikh, MD, PhD, a leading neurologist at University Hospitals discusses his journey into neurology, his groundbreaking research in neuro-ophthalmology, movement disorders, and the application of AI-driven exercise therapy for Parkinson’s disease.

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Elie Saade, MD, MPH, Medical Director of Infection Control at University Hospitals, explains the critical role of infection prevention in healthcare, discusses strategies for reducing hospital-acquired infections, and the impact of interdisciplinary collaboration.

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Professor Mahmoud Ghannoum, a leading expert in medical mycology and microbiome research, shares his pioneering work on the role of fungi in the microbiome and groundbreaking research on the mycobiome’s impact on health, including its role in gut disorders, autism, and cancer.

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James Voos, MD, and Jacob Calcei, MD explore the impact of osteoarthritis, highlighting their team's pioneering work in regenerative therapies to revolutionize musculoskeletal care, and how they collaborate with wearable technology experts to prevent sports injuries and optimize athletic performance.

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Jonathan Shoag, MD, discusses his innovative prostate cancer research aiming to better understand the impact of PSA screening and his groundbreaking work on the genetics of aging.

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David Sheyn, MD, shares his unique career journey to the field of urogynecology, where he now leads innovative research to advance women’s pelvic health through personalized care, AI and cutting-edge technology.

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UH Rainbow Babies & Children's Charles Macias, MD, MPH, discusses his work leading a $48 million grant to improve pediatric disaster readiness, emphasizing the importance of everyday preparedness, national investments in pediatric care, and the significant impact of quality improvement initiatives through structured interventions.

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Jonathan Lass, MD, an expert in corneal transplantation and imaging, shares insights into the groundbreaking work of the UH Eye Image Analysis Reading Centers, advancements in treating various eye conditions and the future of eye care.

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