April 20, 2025 • 25 mins
Weight loss drugs are all over the news at the moment, Ozempic being the most well known. With Wegovy, a similar drug to Ozempic, recently being approved for use in New Zealand it doesn't seem like the talk's going away any time soon.
In this episode Toni chats with Sarah Kennedy and Dr Richard Goldfarb about why weight loss drugs are becoming so popular, how they actually work, and any potential side effects they may cause. Also, they chat about Calocurb, a natural alternative made from hops grown right here in New Zealand.
See omnystudio.com/listener for privacy information.
Mark as Played
Transcript
Episode Transcript
Available transcripts are automatically generated. Complete accuracy is not guaranteed.
Speaker 1 (00:00):
We Need to Talk Conversations on Wellness with Coast FM's
Tony Street.
Speaker 2 (00:06):
Hello, it's great to have you with us for that
We Need to Talk podcast. Weight loss has hit the
headlines once again with the news that weight loss drug
Wegav has been approved by Medsafe for use in New Zealand. Now,
Weigavy is a semiglue tide prescription injection similar to ozempic,
which has already been approved for the purpose of treating
type two diabetes here in New Zealand, and we constantly
(00:27):
hear about this one being used overseas by the Hollywood celebrities.
Sack Sender is the other weight loss drug available in
New Zealand at the moment too. Now one in three
adult New Zealanders over the age of fifteen are classified
as obese. So is this the answer to our growing
problem and what are the other solutions? This week a
group of weight loss experts have gathered to discuss the
(00:49):
use of these GLP one agonists, including doctor Richard Goldfarb,
who is a US doctor and award winning surgeon. And
we also have key we Sarah Kennedy, who's the CEO
of Calo Curb. Now Callo Curb is a New Zealand
government owned piece of technology. And this is basically the
natural version of wegav and of ozempic, which I don't
(01:11):
think is very well known. Now, just to point here,
none of this is sponsored. This is completely out of
our interest and we thought this is a topic that
you'd really want to hear about. So Sarah, let's start
with you. What does it mean to have these injection
drugs like wegav now available in New Zealand because I
feel like New Zealand's been a little bit behind the
eight ball and getting these.
Speaker 3 (01:31):
Oh look, it's fantastic. We have had six gender and
that is a first generation injectible. It's not as effective,
it's a daily injectable, and it's not as effective or
less weight loss than were goov, which is a semi
glue tide. So it's another tool in the toolkit for
(01:52):
doctors here in New Zealand.
Speaker 2 (01:54):
Yeah, which is great news because we know we have
an obesity epidemic. Now, you are the CEO of Calocurb.
How does this natural product which was created in New
Zealand fit into all of this?
Speaker 3 (02:05):
Yeah, look, and it's a fantastic question. Let me go
back a little bit in twenty ten, a group of
very talented scientists employed by the government and Plant and
Food Research had a hypothesis that they would find a
natural plant based extract that suppressed appetite. Now why did
they think that. They think that because they looked historically.
(02:26):
In the fact, in the Highlands of Scotland people chewed
very very bitter berries in times of famine. In the
Kalahari desert tribesmen chew very very bitter cactus before they
go out and hunt. So that was part of it
in some very early work that had been done in animals.
So they had a hypothesis that they would find this.
(02:47):
They got a twenty million dollar grant from the government
and they went about to discover this. So this is
really the genesis of klicerb and a marisate, which is
the naturally strait that we grow here in New Zealand.
So kellocurb stimulates your own natural release of GLP one
(03:09):
versus injecting yourself with a GLP one.
Speaker 2 (03:11):
Okay, So Richard, I'll bring you in here as a
doctor that is prescribing these types of weight loss tools.
How does callocurb work in with the likes of Weigo V.
And how would you prescribe that?
Speaker 4 (03:25):
So I think in three different categories. I would describe
it for patients that want to lose a certain amount
of weight but don't want to go on an injectible,
they're a little bit needle phobic. They would then take
the oral GLP one, which doesn't replace as a synthetic.
It's your own and it stimulates your own GLP one. Therefore,
(03:49):
it's acting to enhance it and make it better and
you can lose weight very naturally. The other aspect is
the injectible doesn't always completely give you that week. Because
you get the injection once a week doesn't give you
that long term effect of it being and working that
entire week. What do you do now it's maybe Thursday
(04:11):
and you get your injections every Sunday. What are you
going to do? You're still hungry. Therefore, we think caliicurb
serves that tremendous purpose in two ways. One is it's
going to stop that hunger pang that you have on Thursday,
Friday and waiting till Sunday. And it's also not going
to allow you to deplete your own GLP one. So
(04:32):
we think that's a great source for it. And the
third reason, which is even more important, is there's a
time when you reach your ideal body weight, you got
to go off your injectables. Now what are you going
to do. So we use caliicub to maintain that weight
loss in those patients and it's been incredibly successful in
the United States.
Speaker 2 (04:52):
How successful, Sirah, give us some statistics. Calicub compared to
your wigavies and eurosipigs.
Speaker 3 (04:59):
So we know that. But we're go v which is
a semi glue tyde will reduce people's calories by an
average of twenty four percent a day. We know from
our clinicals, and remember we have published human clinicals. We
reduce on average a calorie intake by eighteen percent.
Speaker 2 (05:15):
Wow, it's pretty high.
Speaker 3 (05:17):
Yeah it is. And you know we take it an
hour to an hour and a half before lunch and
before dinner. That is to reduce. What we do is
we just make you feel full faster. We are just
super stimulating the release of your own GLP one, so
your own natural GLP one, so you just don't eat
as much. So I give you the example. We all
(05:38):
produce GLP one and that tells us to stop eating
after a while you've had a big dinner and you know,
forty five minutes later you go, oh, I wish I
hadn't eaten that much. It's your gut brain telling you
to stop eating. What we're doing is just telling you
a bit earlier, and we're superstimulating it to a higher level.
So you just eat less, so you can eat. You
(06:00):
just eat less.
Speaker 2 (06:01):
Okay. So I'm a little bit confused, yes, because we
know that in the New Zealand at the moment, if
you want to get saxender or potentially soon we're give
when that is on available, you have to go and
see a doctor. You've got to have a certain BMI
to be able to be to get it. And yet
you're saying with the calicurb you can literally go on
the website and just get it. How is that so?
Speaker 3 (06:22):
Or we're a natural product? I mean fascinating a marisate.
The active ingredient is growing from a specific variety of
hops in Mochueca. Now there's a whole story to how
we didn't target hops. We looked at while not we
the scientists looked at a thousand different extracts. But this
hops is the absolute Eureka we grow it here, we
(06:43):
extract it here, and then it's sent to America to
be made in a delayed release capsule, so it opens
where it's supposed to open. But it is a natural product.
It's literally an extract of hops, a vegetaboil, oil, and
a tiny amount of rosionary which acts as a natural preservative.
So we are a natural product, so you don't need
(07:06):
a prescription. And of course the other thing, if you
think about it, we've been drinking hops because hops are
the flavor and beer for the last I think two
thousand years, so you know, it is a safe it
is a safe additive. It's just that we've found a
way instead of flavoring you beer, we've found a way
(07:27):
that it works with the body to help stimulate that.
Speaker 2 (07:31):
Richard, how has this been received in the States, Because
this is a pretty big deal for New Zealand, right.
Speaker 4 (07:36):
Yes it is, and the United States has really received
this tremendously. We have a lot of our colleagues that
have started a lot of weight loss programs in order
to treat the obesity crisis, which is absolutely a worldwide crisis,
and obviously in the United States it's always bigger and
better and these crazy things, so we really did not
(07:58):
have a solution until the GLP ones we're out there.
I mean, we have other stimulants you know, that cause
other side effects, but the GLP ones for the most part,
have been safe. However, there are some gi manifestations forbidgut,
pancreatitis or other issues with it, where we've seen much
(08:21):
less of those side effects with the Cali curb, which
is tremendous and we feel that they're very, very useful
to treat the obesity crisis. Just look at the numbers,
how tremendous it is even in the United States and worldwide,
but they're all missing that part, and we feel Cali
curb really really completes the whole gamut as far as
(08:44):
really reducing your weight, eating healthier, hopefully living longer, and
all these wonderful manifestations that should happen from it.
Speaker 5 (08:53):
This is we need to talk with Tony Street.
Speaker 2 (08:56):
Sarah tell us about your personal situation because I read
that you have had in the past a dysfunctional and
unhealthy relationship with food since you were ten years old.
Can you just talk us through that and how you
managed to I mean, I'm looking at a very trim
woman today.
Speaker 3 (09:12):
Yeah, I think any founder to found anything, I think
you have to be truly mad. So when I was
approached in twenty and seventeen with his science, I think
it hit a real personal note for me. I've had
a love hate relationship with food my whole life.
Speaker 2 (09:29):
You know.
Speaker 3 (09:29):
I first went on a diet when I was ten
years old. And I think many people, many if women,
maybe men as well, would you know loving food but
then hating yourself yo yo diet and doing all of
those things. And when I say, you love the food,
but you hate yourself for eating it, you hate yourself
for losing control, you do all of that, And I
can honestly say, I mean, I take caloricub every day.
(09:51):
It's just my maintenance program. But I now am at
peace with food and that takes that noise out of
your head. Happy with myself and I'm happy with food.
I can eat food, I just don't eat as much
so it don't binge yo yo oh. I'm going to
try this start. I'm going to try the start. Oh
my god, I love it.
Speaker 2 (10:11):
It surprises me that more people in this country don't
know about this, and particularly given it's a new Zealand
piece of technology. Why do you think that is? Why
are we not singing this from the rooftops?
Speaker 3 (10:23):
Well, I think there's a number of reasons, and let
me go back. I think it's fantastic that grigovi has
been approved in New Zealand because now we're starting to
talk about it, and we're starting to talk about the
physiology of weight management, and people always say, and there
still is this doctrine out there about willpower and eating willpower.
(10:44):
I will tell you we are our hunger is driven
by hormones. So I think I said to you before,
if you reduce your calories by twenty five percent a day,
your hunger will double over four months because your body
thinks you're going into a famine. So you'll like think
I've got willpower, I've got willpower. You put stress, lack
(11:07):
of sleep, all of those things and your willpower or go.
So why have we not here in New Zealand? So
we Govy was approved in the US in twenty twenty one.
Nova noticed, the company that owns with gov spent a
billion dollars on marketing in the US. They took out
(11:27):
to dinner two hundred and thirty nine thousand doctors to
talk to them about the physiology of weight management or
weight loss. So they paved the way for us in
the US so we could talk about we're a natural
GLP one activator, that's a synthetic GLP one. We can
(11:48):
be used in combination or alternative. That discussion has really
just started in New Zealand, and really up until that point,
really what were you going to discuss the New Zealand.
So this to us is fantastic. It is opening the
discussion up about and I want everyone listening to think,
(12:08):
do not think it's your fault. Do not think it's
will Parer, because that is part of that love hate relationship,
and it is not. It is your body, which was
an asset for us through evolution. It is your body
saying you could be going into a famine eat now.
Speaker 2 (12:24):
And such a vicious cycle as well. And exactly what
you're saying. The statistics, it's something ridiculous like ninety five
percent of people will put back the weight they lose
within two years, right.
Speaker 3 (12:35):
Even more than that. I read one yesterday and it
is it is and that is because your body is
fighting you all the time. It thinks it's going into
a famine, So you need to have a in the injectibles.
That is the problem. You come off the injectibles, natural
GLP one is down low, it has to come back
up again. That's a real problem. And the trouble is
(12:59):
it puts you off off food the injections. That's not
a problem. But the thing is you have to get
into a healthy rhythm of eating and to try and
take that noise out of your head.
Speaker 2 (13:10):
And that's why it's good to have professional sort of
guiding you through it. Richard, you are someone that has
also recommended and carried out batriotic surgeries, and I feel
like that was before these injectibles. So where does that
now fit into the mix? Is it still a viable
option for people to go down the surgery routes.
Speaker 4 (13:29):
We think some of the grossly morbid obese patients that
are still an ideal situation, but certainly not nearly the
amount of cases that we would do without the GLP ones.
And we find that it's obviously safer than having surgery
a lot of complications with it. We try to do
it now it's called laparoscopically, where we don't visualize everything
(13:52):
and those big blood vessels up there. You can really
get a lot of complications. Although our technology is improved,
complication rate has not really reduced that much. And unless
we really want to take that risk, you know, there's
anesthesia risk. We feel that the alternative of the semiglue
tides along with calicurb have really breaking loose the treatment
(14:16):
for obesity in a much better, safer way.
Speaker 2 (14:19):
Let's talk about the side effects, because that is the
thing that might stop people from going there. And I
think there have been some high profile people like I
remember Amy Schumer came out and said, look, I tried
O's impac and it made me so foggy I couldn't
play with my kids. I see she's now reversed that
and she's going she's on wigavy again and said, actually
this one suits me better. Can everyone tolerate these or
(14:41):
are there going to be some people that just can't
deal with them?
Speaker 4 (14:44):
There are a small percentage, and it's really a small
percentage of patients that cannot tolerate it at all. There
are some GI side effects, guesstro intestinal side effects such
as the worst pancreatitiscuff Forbidge get that. There's some gallbladder
issues and some GI nausea issues that are just overwhelming,
but for the most part, most of the patients will
(15:07):
tolerate it. What I find interesting is that the patients
that take the injectable do have a significantly more side
effect ratio than we've seen in our calic patients. And
I think that's important to say, And I think what
else is really important to emphasize. You're putting something synthetic
in there, so it drives your own inherent GLP one
(15:30):
levels to a low, low level, and we don't want
to have that. So the fact that calicur will stimulate
your own inherent GLP one is really an important fast
factor in treating the overall condition.
Speaker 2 (15:43):
Sarah, how much do we know about the long terms
effects of this or side effects? Because that's pretty new, right.
Speaker 3 (15:50):
Are you talking kellikub or JLP one? We both OKAYLP
one's will know. Look, you know they've been around since
what two thousand and five, so twenty years because they
originally used for TAP two diabetes. And interesting with that,
they actually noticed people were losing weight and they're like, oh,
something else is happening, And there was a whole lot
more mechanisms that went into it. So you know, and
(16:14):
they would say, you know, like any chronic disease and
obesity is it is a long term, you know, long
term use, so we think they're fairly safe. I'm yet
to meet a doctor, but you know, I may meet
one who really wants to keep their patients on for life.
You know, maybe in chronic obesity, maybe in morbid obesity,
but calicob I'd go back to the point and say,
(16:37):
we've been drinking beer for two thousand years, we've had
hops in our beer, I think for nine hundred years,
so very safe. We're just completing another human clinical trial
now where you know, I'll be able to tell you
more in probably four or five months. But we think,
our scientists believe that we upregulate these cells in our intestine,
(17:00):
so we're actually making your gut brain access better. So
if you come off CALORICUB, we've actually made this gut
brain access work better. And if you kind of think
about it, we're exercising these little l cells in your intestine,
so whenever you exercise something, you know they produce better.
So that's a hypothesis. So I have no worry, and
(17:23):
you know I go on and off calor CUB. Sometimes
you know, not for any reason other than it might
be the weekend and I forget and it's.
Speaker 2 (17:32):
Perfect like that and that works.
Speaker 5 (17:33):
Fine, you're listening. Do we need a talk with Tony Street?
Speaker 2 (17:39):
One of the debates that I've had with a couple
of friends of mine who are dietitians. You know, they
see the absolute need for it in some cases, but
their concern is that people that are eating less aren't
going to be getting a balanced diet and not have
enough of your proteins and your balance of good fats
because you don't have that same desire to eat. What
would you say to that?
Speaker 3 (17:59):
Oh, look, I think they have a good point, which
is why we market and sell through practitioners, and practitioners
go from doctors to nutritionists to all of this dieticians.
And yes, because it is a tool and a toolkit,
you know, as if you go from ten donuts to
eight donuts, you're not going to make any difference, right.
(18:21):
You want to you want to have a balanced start
and particularly up your protein, and if it's anything, we
don't on average we don't get enough protein a day
and it's really hard to get that amount of protein,
particularly for women.
Speaker 2 (18:36):
Women are forty.
Speaker 3 (18:37):
Woman over forty, you know, we need to be eating
like one hundred to one hundred and twenty grams of
protein per day. And you're like, I have two eggs.
Do you know how much protein that is? Twelve grams?
So it is hard. You need to be eating and
and then people, so it's expensive. I don't want to
cook it, all of those things all. And that's why
I do say, you know, protein drinks are quite convenient. However,
(18:58):
I'm marketing someone else now, No, no, I would say
it's a tool in the tool. The other thing to
remember is, particularly for women over forty, exercise is unlikely
to make you lose a lot of weight, but strength
training is absolute. You want to you will your muscle
mass decreases as you get older. So don't think you
(19:19):
have to run a marathon. Just do a bit of
strength training and you don't have to bulk up, spend
two hours at the gym, but do do something. Do
those get those muscles working, do some weights in your arms.
And in fact, I'm going to hand it over to
Richard because in their clinic you actually that's part of
your whole weight loss program.
Speaker 2 (19:38):
That's really interesting you say that because we have had
several experts on that We Need to Talk podcast, including
a physiologist Stacy Simms. Oh, she's brilliant and Stacy absolutely
sinks the praises of gym workouts and that lean muscle mass.
Speaker 4 (19:54):
Richard, Yes, that's true. We have a very interesting weight
loss program we called a touch weight loss program. So
if you borrow some of the data from the most
successful weight loss program ever in the world was Weight Watchers,
because you had to be accountable weekly, so people go, oh,
I got to be accountable. I don't want to go
in and show my gain weight. So that makes the
(20:16):
psychologic aspect work. The other thing is most of these
people that are grossly obese, even when they do lose
they're not motivated enough to go back to the gym
as Sarah indicated and do some strengthening exercises. So we
have some devices that are in all over the world
(20:37):
that will help build some muscle because you do lose
some muscle mass when you lose weight. So we actually
when they reach their ideal body weight, treat them with
that particular device to help them. We also we work
with a gymnasium that's near our practice, and what we
do is we have and they're always trying to get
new clients because it's such a competitive market. We actually
(21:00):
have our person that's really in charge of our weight
loss program go over to the gym with them and
actually show them and demonstrate. They get their three free
treatments to the gym, and then the gym wants to
grab them and make them members. But if they've had
three successful treatments with our provider, then they feel like, wow,
I can really do this, and that's good for the gym,
(21:22):
it's good for us. Okay, going because now that's how
we get such great, great results.
Speaker 2 (21:27):
What's this device you speak of.
Speaker 4 (21:28):
It's called m sculpt Neo is the first one that
came out, and it basically is high intensity focused to
electromagnetic energy. What it really means is it stimulates to
contract your muscles. For example, is you're on the device
and they put these paddles on you and it's equivalent
to do in twenty thousand sit ups in thirty minutes,
(21:50):
which is impossible for you to do. And the other
part of it is it bypasses the aspect of lactic
acid release. Therefore you don't feel that burn when you
work out at the gym. So by passing that it
actually will build the muscles, and then the actinomyacin in
the muscle will release, and therefore the muscle will hypertrophy
(22:12):
and you will look better and feel better. And it's
a tremendous another tool in the armentarium of weight development
and body shaping.
Speaker 2 (22:22):
Isn't it amazing you think you come into a podcast
knowing all there is to know about weight loss and
these all these things I had no idea about just
finding a comment from you, Richard on where weight loss
globally is at the moment in terms of breakthroughs, because
I feel like this is just the most incredible place
that the world has been in and fixing this obesity pandemic.
Speaker 4 (22:43):
So as we know, obesity is really the common denominator
with heart disease, diabetes, and cancer, so we feel like
we have to make an impact worldwide. And we think
that the manifestations of the these combination drugs have been
helpful as another tool to really decrease in the ob
(23:06):
city situation, and we think we've made a tremendous upswing
in that aspect. I think more people are aware of
the fact they associated ob city with these disease processes
and they're realizing, you know, people want not only length
of life, but they want quality of life. So therefore,
we really do see that the drugs have made a
(23:27):
major impact, which is a great tool for us as physicians,
but we really think they're missing that one aspect which
I really will tell you Cala Curb has really fit
that bill beautifully, and I proved it because we've done it,
and we've proved that that's the best method to do it.
Our results are really really spectacular.
Speaker 3 (23:48):
Well, we would say, you know, in calicab, we would
envisions envisage a world without obesity. But remember every day,
you know, your brain is still fighting you every day.
So you know, like for me, helicub just allows me
to walk past that muffin at morning tea. It allows
me to walk past you know, I'm full after dinner.
(24:09):
I don't need dessert or I'm not going to have
a biscuit later on the fact that.
Speaker 4 (24:13):
The calicurb will give you that four to six hours.
What happens is and we've done this study in the
United States, and I know we've done it in some
of the other country surrounding the United States. That nighttime
eating is the worst culprit. You have dinner, you're gonna
sit down, you're gonna watch television, you want to munch
(24:34):
on something. A lot of people aren't going to grab
a carrot and those healthy things. People are going to
grab chips and those type of things. The fact that
the half life of calicurb, how long it lasts if
you take it before dinner, gives you that four to
six hours. Therefore, they're not craving those chips at night.
They don't have a full belly full of bad you know,
(24:56):
foods that are just sitting there causing you to put
on the pound. And I think that curb itself has
made a tremendous impact. I know in our patients that
we've studied, it's been tremendous.
Speaker 3 (25:08):
Just remember it's not all about weight loss. It is
about weight management or weight maintenance. So you just we
are surrounded by food every day and our brain is
telling us. So if you can just quieten some of
that down, and you know, this is the other thing.
There's noise in your head and how many people, well
most of our comments come back, are you take the
(25:31):
noise out of my head.
Speaker 5 (25:33):
We need to talk with COASTFMS Tony Street.
Speaker 1 (25:36):
If you enjoyed the podcast, click to share with family
or friends. To get in touch, email we need to
talk at gastonline, dot co, dot mz
We Need to Talk Conversations on Wellness with Coast FM's
Tony Street.
Speaker 2 (00:06):
Hello, it's great to have you with us for that
We Need to Talk podcast. Weight loss has hit the
headlines once again with the news that weight loss drug
Wegav has been approved by Medsafe for use in New Zealand. Now,
Weigavy is a semiglue tide prescription injection similar to ozempic,
which has already been approved for the purpose of treating
type two diabetes here in New Zealand, and we constantly
(00:27):
hear about this one being used overseas by the Hollywood celebrities.
Sack Sender is the other weight loss drug available in
New Zealand at the moment too. Now one in three
adult New Zealanders over the age of fifteen are classified
as obese. So is this the answer to our growing
problem and what are the other solutions? This week a
group of weight loss experts have gathered to discuss the
(00:49):
use of these GLP one agonists, including doctor Richard Goldfarb,
who is a US doctor and award winning surgeon. And
we also have key we Sarah Kennedy, who's the CEO
of Calo Curb. Now Callo Curb is a New Zealand
government owned piece of technology. And this is basically the
natural version of wegav and of ozempic, which I don't
(01:11):
think is very well known. Now, just to point here,
none of this is sponsored. This is completely out of
our interest and we thought this is a topic that
you'd really want to hear about. So Sarah, let's start
with you. What does it mean to have these injection
drugs like wegav now available in New Zealand because I
feel like New Zealand's been a little bit behind the
eight ball and getting these.
Speaker 3 (01:31):
Oh look, it's fantastic. We have had six gender and
that is a first generation injectible. It's not as effective,
it's a daily injectable, and it's not as effective or
less weight loss than were goov, which is a semi
glue tide. So it's another tool in the toolkit for
(01:52):
doctors here in New Zealand.
Speaker 2 (01:54):
Yeah, which is great news because we know we have
an obesity epidemic. Now, you are the CEO of Calocurb.
How does this natural product which was created in New
Zealand fit into all of this?
Speaker 3 (02:05):
Yeah, look, and it's a fantastic question. Let me go
back a little bit in twenty ten, a group of
very talented scientists employed by the government and Plant and
Food Research had a hypothesis that they would find a
natural plant based extract that suppressed appetite. Now why did
they think that. They think that because they looked historically.
(02:26):
In the fact, in the Highlands of Scotland people chewed
very very bitter berries in times of famine. In the
Kalahari desert tribesmen chew very very bitter cactus before they
go out and hunt. So that was part of it
in some very early work that had been done in animals.
So they had a hypothesis that they would find this.
(02:47):
They got a twenty million dollar grant from the government
and they went about to discover this. So this is
really the genesis of klicerb and a marisate, which is
the naturally strait that we grow here in New Zealand.
So kellocurb stimulates your own natural release of GLP one
(03:09):
versus injecting yourself with a GLP one.
Speaker 2 (03:11):
Okay, So Richard, I'll bring you in here as a
doctor that is prescribing these types of weight loss tools.
How does callocurb work in with the likes of Weigo V.
And how would you prescribe that?
Speaker 4 (03:25):
So I think in three different categories. I would describe
it for patients that want to lose a certain amount
of weight but don't want to go on an injectible,
they're a little bit needle phobic. They would then take
the oral GLP one, which doesn't replace as a synthetic.
It's your own and it stimulates your own GLP one. Therefore,
(03:49):
it's acting to enhance it and make it better and
you can lose weight very naturally. The other aspect is
the injectible doesn't always completely give you that week. Because
you get the injection once a week doesn't give you
that long term effect of it being and working that
entire week. What do you do now it's maybe Thursday
(04:11):
and you get your injections every Sunday. What are you
going to do? You're still hungry. Therefore, we think caliicurb
serves that tremendous purpose in two ways. One is it's
going to stop that hunger pang that you have on Thursday,
Friday and waiting till Sunday. And it's also not going
to allow you to deplete your own GLP one. So
(04:32):
we think that's a great source for it. And the
third reason, which is even more important, is there's a
time when you reach your ideal body weight, you got
to go off your injectables. Now what are you going
to do. So we use caliicub to maintain that weight
loss in those patients and it's been incredibly successful in
the United States.
Speaker 2 (04:52):
How successful, Sirah, give us some statistics. Calicub compared to
your wigavies and eurosipigs.
Speaker 3 (04:59):
So we know that. But we're go v which is
a semi glue tyde will reduce people's calories by an
average of twenty four percent a day. We know from
our clinicals, and remember we have published human clinicals. We
reduce on average a calorie intake by eighteen percent.
Speaker 2 (05:15):
Wow, it's pretty high.
Speaker 3 (05:17):
Yeah it is. And you know we take it an
hour to an hour and a half before lunch and
before dinner. That is to reduce. What we do is
we just make you feel full faster. We are just
super stimulating the release of your own GLP one, so
your own natural GLP one, so you just don't eat
as much. So I give you the example. We all
(05:38):
produce GLP one and that tells us to stop eating
after a while you've had a big dinner and you know,
forty five minutes later you go, oh, I wish I
hadn't eaten that much. It's your gut brain telling you
to stop eating. What we're doing is just telling you
a bit earlier, and we're superstimulating it to a higher level.
So you just eat less, so you can eat. You
(06:00):
just eat less.
Speaker 2 (06:01):
Okay. So I'm a little bit confused, yes, because we
know that in the New Zealand at the moment, if
you want to get saxender or potentially soon we're give
when that is on available, you have to go and
see a doctor. You've got to have a certain BMI
to be able to be to get it. And yet
you're saying with the calicurb you can literally go on
the website and just get it. How is that so?
Speaker 3 (06:22):
Or we're a natural product? I mean fascinating a marisate.
The active ingredient is growing from a specific variety of
hops in Mochueca. Now there's a whole story to how
we didn't target hops. We looked at while not we
the scientists looked at a thousand different extracts. But this
hops is the absolute Eureka we grow it here, we
(06:43):
extract it here, and then it's sent to America to
be made in a delayed release capsule, so it opens
where it's supposed to open. But it is a natural product.
It's literally an extract of hops, a vegetaboil, oil, and
a tiny amount of rosionary which acts as a natural preservative.
So we are a natural product, so you don't need
(07:06):
a prescription. And of course the other thing, if you
think about it, we've been drinking hops because hops are
the flavor and beer for the last I think two
thousand years, so you know, it is a safe it
is a safe additive. It's just that we've found a
way instead of flavoring you beer, we've found a way
(07:27):
that it works with the body to help stimulate that.
Speaker 2 (07:31):
Richard, how has this been received in the States, Because
this is a pretty big deal for New Zealand, right.
Speaker 4 (07:36):
Yes it is, and the United States has really received
this tremendously. We have a lot of our colleagues that
have started a lot of weight loss programs in order
to treat the obesity crisis, which is absolutely a worldwide crisis,
and obviously in the United States it's always bigger and
better and these crazy things, so we really did not
(07:58):
have a solution until the GLP ones we're out there.
I mean, we have other stimulants you know, that cause
other side effects, but the GLP ones for the most part,
have been safe. However, there are some gi manifestations forbidgut,
pancreatitis or other issues with it, where we've seen much
(08:21):
less of those side effects with the Cali curb, which
is tremendous and we feel that they're very, very useful
to treat the obesity crisis. Just look at the numbers,
how tremendous it is even in the United States and worldwide,
but they're all missing that part, and we feel Cali
curb really really completes the whole gamut as far as
(08:44):
really reducing your weight, eating healthier, hopefully living longer, and
all these wonderful manifestations that should happen from it.
Speaker 5 (08:53):
This is we need to talk with Tony Street.
Speaker 2 (08:56):
Sarah tell us about your personal situation because I read
that you have had in the past a dysfunctional and
unhealthy relationship with food since you were ten years old.
Can you just talk us through that and how you
managed to I mean, I'm looking at a very trim
woman today.
Speaker 3 (09:12):
Yeah, I think any founder to found anything, I think
you have to be truly mad. So when I was
approached in twenty and seventeen with his science, I think
it hit a real personal note for me. I've had
a love hate relationship with food my whole life.
Speaker 2 (09:29):
You know.
Speaker 3 (09:29):
I first went on a diet when I was ten
years old. And I think many people, many if women,
maybe men as well, would you know loving food but
then hating yourself yo yo diet and doing all of
those things. And when I say, you love the food,
but you hate yourself for eating it, you hate yourself
for losing control, you do all of that, And I
can honestly say, I mean, I take caloricub every day.
(09:51):
It's just my maintenance program. But I now am at
peace with food and that takes that noise out of
your head. Happy with myself and I'm happy with food.
I can eat food, I just don't eat as much
so it don't binge yo yo oh. I'm going to
try this start. I'm going to try the start. Oh
my god, I love it.
Speaker 2 (10:11):
It surprises me that more people in this country don't
know about this, and particularly given it's a new Zealand
piece of technology. Why do you think that is? Why
are we not singing this from the rooftops?
Speaker 3 (10:23):
Well, I think there's a number of reasons, and let
me go back. I think it's fantastic that grigovi has
been approved in New Zealand because now we're starting to
talk about it, and we're starting to talk about the
physiology of weight management, and people always say, and there
still is this doctrine out there about willpower and eating willpower.
(10:44):
I will tell you we are our hunger is driven
by hormones. So I think I said to you before,
if you reduce your calories by twenty five percent a day,
your hunger will double over four months because your body
thinks you're going into a famine. So you'll like think
I've got willpower, I've got willpower. You put stress, lack
(11:07):
of sleep, all of those things and your willpower or go.
So why have we not here in New Zealand? So
we Govy was approved in the US in twenty twenty one.
Nova noticed, the company that owns with gov spent a
billion dollars on marketing in the US. They took out
(11:27):
to dinner two hundred and thirty nine thousand doctors to
talk to them about the physiology of weight management or
weight loss. So they paved the way for us in
the US so we could talk about we're a natural
GLP one activator, that's a synthetic GLP one. We can
(11:48):
be used in combination or alternative. That discussion has really
just started in New Zealand, and really up until that point,
really what were you going to discuss the New Zealand.
So this to us is fantastic. It is opening the
discussion up about and I want everyone listening to think,
(12:08):
do not think it's your fault. Do not think it's
will Parer, because that is part of that love hate relationship,
and it is not. It is your body, which was
an asset for us through evolution. It is your body
saying you could be going into a famine eat now.
Speaker 2 (12:24):
And such a vicious cycle as well. And exactly what
you're saying. The statistics, it's something ridiculous like ninety five
percent of people will put back the weight they lose
within two years, right.
Speaker 3 (12:35):
Even more than that. I read one yesterday and it
is it is and that is because your body is
fighting you all the time. It thinks it's going into
a famine, So you need to have a in the injectibles.
That is the problem. You come off the injectibles, natural
GLP one is down low, it has to come back
up again. That's a real problem. And the trouble is
(12:59):
it puts you off off food the injections. That's not
a problem. But the thing is you have to get
into a healthy rhythm of eating and to try and
take that noise out of your head.
Speaker 2 (13:10):
And that's why it's good to have professional sort of
guiding you through it. Richard, you are someone that has
also recommended and carried out batriotic surgeries, and I feel
like that was before these injectibles. So where does that
now fit into the mix? Is it still a viable
option for people to go down the surgery routes.
Speaker 4 (13:29):
We think some of the grossly morbid obese patients that
are still an ideal situation, but certainly not nearly the
amount of cases that we would do without the GLP ones.
And we find that it's obviously safer than having surgery
a lot of complications with it. We try to do
it now it's called laparoscopically, where we don't visualize everything
(13:52):
and those big blood vessels up there. You can really
get a lot of complications. Although our technology is improved,
complication rate has not really reduced that much. And unless
we really want to take that risk, you know, there's
anesthesia risk. We feel that the alternative of the semiglue
tides along with calicurb have really breaking loose the treatment
(14:16):
for obesity in a much better, safer way.
Speaker 2 (14:19):
Let's talk about the side effects, because that is the
thing that might stop people from going there. And I
think there have been some high profile people like I
remember Amy Schumer came out and said, look, I tried
O's impac and it made me so foggy I couldn't
play with my kids. I see she's now reversed that
and she's going she's on wigavy again and said, actually
this one suits me better. Can everyone tolerate these or
(14:41):
are there going to be some people that just can't
deal with them?
Speaker 4 (14:44):
There are a small percentage, and it's really a small
percentage of patients that cannot tolerate it at all. There
are some GI side effects, guesstro intestinal side effects such
as the worst pancreatitiscuff Forbidge get that. There's some gallbladder
issues and some GI nausea issues that are just overwhelming,
but for the most part, most of the patients will
(15:07):
tolerate it. What I find interesting is that the patients
that take the injectable do have a significantly more side
effect ratio than we've seen in our calic patients. And
I think that's important to say, And I think what
else is really important to emphasize. You're putting something synthetic
in there, so it drives your own inherent GLP one
(15:30):
levels to a low, low level, and we don't want
to have that. So the fact that calicur will stimulate
your own inherent GLP one is really an important fast
factor in treating the overall condition.
Speaker 2 (15:43):
Sarah, how much do we know about the long terms
effects of this or side effects? Because that's pretty new, right.
Speaker 3 (15:50):
Are you talking kellikub or JLP one? We both OKAYLP
one's will know. Look, you know they've been around since
what two thousand and five, so twenty years because they
originally used for TAP two diabetes. And interesting with that,
they actually noticed people were losing weight and they're like, oh,
something else is happening, And there was a whole lot
more mechanisms that went into it. So you know, and
(16:14):
they would say, you know, like any chronic disease and
obesity is it is a long term, you know, long
term use, so we think they're fairly safe. I'm yet
to meet a doctor, but you know, I may meet
one who really wants to keep their patients on for life.
You know, maybe in chronic obesity, maybe in morbid obesity,
but calicob I'd go back to the point and say,
(16:37):
we've been drinking beer for two thousand years, we've had
hops in our beer, I think for nine hundred years,
so very safe. We're just completing another human clinical trial
now where you know, I'll be able to tell you
more in probably four or five months. But we think,
our scientists believe that we upregulate these cells in our intestine,
(17:00):
so we're actually making your gut brain access better. So
if you come off CALORICUB, we've actually made this gut
brain access work better. And if you kind of think
about it, we're exercising these little l cells in your intestine,
so whenever you exercise something, you know they produce better.
So that's a hypothesis. So I have no worry, and
(17:23):
you know I go on and off calor CUB. Sometimes
you know, not for any reason other than it might
be the weekend and I forget and it's.
Speaker 2 (17:32):
Perfect like that and that works.
Speaker 5 (17:33):
Fine, you're listening. Do we need a talk with Tony Street?
Speaker 2 (17:39):
One of the debates that I've had with a couple
of friends of mine who are dietitians. You know, they
see the absolute need for it in some cases, but
their concern is that people that are eating less aren't
going to be getting a balanced diet and not have
enough of your proteins and your balance of good fats
because you don't have that same desire to eat. What
would you say to that?
Speaker 3 (17:59):
Oh, look, I think they have a good point, which
is why we market and sell through practitioners, and practitioners
go from doctors to nutritionists to all of this dieticians.
And yes, because it is a tool and a toolkit,
you know, as if you go from ten donuts to
eight donuts, you're not going to make any difference, right.
(18:21):
You want to you want to have a balanced start
and particularly up your protein, and if it's anything, we
don't on average we don't get enough protein a day
and it's really hard to get that amount of protein,
particularly for women.
Speaker 2 (18:36):
Women are forty.
Speaker 3 (18:37):
Woman over forty, you know, we need to be eating
like one hundred to one hundred and twenty grams of
protein per day. And you're like, I have two eggs.
Do you know how much protein that is? Twelve grams?
So it is hard. You need to be eating and
and then people, so it's expensive. I don't want to
cook it, all of those things all. And that's why
I do say, you know, protein drinks are quite convenient. However,
(18:58):
I'm marketing someone else now, No, no, I would say
it's a tool in the tool. The other thing to
remember is, particularly for women over forty, exercise is unlikely
to make you lose a lot of weight, but strength
training is absolute. You want to you will your muscle
mass decreases as you get older. So don't think you
(19:19):
have to run a marathon. Just do a bit of
strength training and you don't have to bulk up, spend
two hours at the gym, but do do something. Do
those get those muscles working, do some weights in your arms.
And in fact, I'm going to hand it over to
Richard because in their clinic you actually that's part of
your whole weight loss program.
Speaker 2 (19:38):
That's really interesting you say that because we have had
several experts on that We Need to Talk podcast, including
a physiologist Stacy Simms. Oh, she's brilliant and Stacy absolutely
sinks the praises of gym workouts and that lean muscle mass.
Speaker 4 (19:54):
Richard, Yes, that's true. We have a very interesting weight
loss program we called a touch weight loss program. So
if you borrow some of the data from the most
successful weight loss program ever in the world was Weight Watchers,
because you had to be accountable weekly, so people go, oh,
I got to be accountable. I don't want to go
in and show my gain weight. So that makes the
(20:16):
psychologic aspect work. The other thing is most of these
people that are grossly obese, even when they do lose
they're not motivated enough to go back to the gym
as Sarah indicated and do some strengthening exercises. So we
have some devices that are in all over the world
(20:37):
that will help build some muscle because you do lose
some muscle mass when you lose weight. So we actually
when they reach their ideal body weight, treat them with
that particular device to help them. We also we work
with a gymnasium that's near our practice, and what we
do is we have and they're always trying to get
new clients because it's such a competitive market. We actually
(21:00):
have our person that's really in charge of our weight
loss program go over to the gym with them and
actually show them and demonstrate. They get their three free
treatments to the gym, and then the gym wants to
grab them and make them members. But if they've had
three successful treatments with our provider, then they feel like, wow,
I can really do this, and that's good for the gym,
(21:22):
it's good for us. Okay, going because now that's how
we get such great, great results.
Speaker 2 (21:27):
What's this device you speak of.
Speaker 4 (21:28):
It's called m sculpt Neo is the first one that
came out, and it basically is high intensity focused to
electromagnetic energy. What it really means is it stimulates to
contract your muscles. For example, is you're on the device
and they put these paddles on you and it's equivalent
to do in twenty thousand sit ups in thirty minutes,
(21:50):
which is impossible for you to do. And the other
part of it is it bypasses the aspect of lactic
acid release. Therefore you don't feel that burn when you
work out at the gym. So by passing that it
actually will build the muscles, and then the actinomyacin in
the muscle will release, and therefore the muscle will hypertrophy
(22:12):
and you will look better and feel better. And it's
a tremendous another tool in the armentarium of weight development
and body shaping.
Speaker 2 (22:22):
Isn't it amazing you think you come into a podcast
knowing all there is to know about weight loss and
these all these things I had no idea about just
finding a comment from you, Richard on where weight loss
globally is at the moment in terms of breakthroughs, because
I feel like this is just the most incredible place
that the world has been in and fixing this obesity pandemic.
Speaker 4 (22:43):
So as we know, obesity is really the common denominator
with heart disease, diabetes, and cancer, so we feel like
we have to make an impact worldwide. And we think
that the manifestations of the these combination drugs have been
helpful as another tool to really decrease in the ob
(23:06):
city situation, and we think we've made a tremendous upswing
in that aspect. I think more people are aware of
the fact they associated ob city with these disease processes
and they're realizing, you know, people want not only length
of life, but they want quality of life. So therefore,
we really do see that the drugs have made a
(23:27):
major impact, which is a great tool for us as physicians,
but we really think they're missing that one aspect which
I really will tell you Cala Curb has really fit
that bill beautifully, and I proved it because we've done it,
and we've proved that that's the best method to do it.
Our results are really really spectacular.
Speaker 3 (23:48):
Well, we would say, you know, in calicab, we would
envisions envisage a world without obesity. But remember every day,
you know, your brain is still fighting you every day.
So you know, like for me, helicub just allows me
to walk past that muffin at morning tea. It allows
me to walk past you know, I'm full after dinner.
(24:09):
I don't need dessert or I'm not going to have
a biscuit later on the fact that.
Speaker 4 (24:13):
The calicurb will give you that four to six hours.
What happens is and we've done this study in the
United States, and I know we've done it in some
of the other country surrounding the United States. That nighttime
eating is the worst culprit. You have dinner, you're gonna
sit down, you're gonna watch television, you want to munch
(24:34):
on something. A lot of people aren't going to grab
a carrot and those healthy things. People are going to
grab chips and those type of things. The fact that
the half life of calicurb, how long it lasts if
you take it before dinner, gives you that four to
six hours. Therefore, they're not craving those chips at night.
They don't have a full belly full of bad you know,
(24:56):
foods that are just sitting there causing you to put
on the pound. And I think that curb itself has
made a tremendous impact. I know in our patients that
we've studied, it's been tremendous.
Speaker 3 (25:08):
Just remember it's not all about weight loss. It is
about weight management or weight maintenance. So you just we
are surrounded by food every day and our brain is
telling us. So if you can just quieten some of
that down, and you know, this is the other thing.
There's noise in your head and how many people, well
most of our comments come back, are you take the
(25:31):
noise out of my head.
Speaker 5 (25:33):
We need to talk with COASTFMS Tony Street.
Speaker 1 (25:36):
If you enjoyed the podcast, click to share with family
or friends. To get in touch, email we need to
talk at gastonline, dot co, dot mz
Popular Podcasts
40s and Free Agents: NFL Draft Season
Daniel Jeremiah of Move the Sticks and Gregg Rosenthal of NFL Daily join forces to break down every team's needs this offseason.
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
The Bobby Bones Show
Listen to 'The Bobby Bones Show' by downloading the daily full replay.