From Our Neurons to Yours

Last month we saw a big shift in the federal government’s approach to psychedelic medicine.

Specifically, following an executive order by President Trump, the FDA announced it is fast-tracking its review of several clinical trials of psychedelic drugs for patients with mental health disorders. The executive order also directed more funds towards psychedelic research and a review of psychedelics’ status as highly restricted Schedule ...

Today’s episode is about the neuroscience of hard work—or maybe more specifically, the value we place on hard work.

There’s something different about hiking to the top of a mountain versus taking a helicopter. The view from the top is exactly the same, but if you’ve done the hard slog to get there, the payoff is going to be much more rewarding. 

The question is, how does the brain know the difference? To answer this, we need to take ...

Traditionally, we think of Parkinson's as a movement disorder—defined by slowed movement, stiff muscles, and involuntary shaking. But it turns out there are other symptoms that appear years or even decades before movement problems bring patients to the clinic: sleep disturbances, chronic constipation, and loss of smell.

For today's guest, these early symptoms represent an incredible opportunity to understand where Parkinso...

What if we could make the brain see-through? 

It sounds like science fiction, but it could revolutionize how we study the brain. 

Today on the show, we're talking with Guosong Hong, a faculty scholar here at the Wu Tsai Neurosciences Institute who has a unique reputation for developing creative techniques that literally shed light on the brain—from using fluorescent nanomaterials and focused ultrasound to create a virtual flashl...

Our memories and senses are deeply connected—like how a favorite song can recreate a whole glorious teenage summer. It turns out this relationship might extend beyond our five external senses to include our internal senses: the signals telling us what's happening inside our bodies, sometimes beyond the veil of conscious perception.

New research by Wu Tsai Neurosciences Institute affiliate Christoph Thaiss suggests that losing t...

Today on the show, why do some of us age faster than others? Why do some of us grow old and die before our time while others seem to simply endure? And most of us have probably wondered at one point or another, which track am I on? 

Turns out it might be possible to predict the whole trajectory of an animal's life at a surprisingly young age, just by looking closely at subtle patterns of behavior. That's the conclusion of ...

We know shockingly little about what goes on in a mother’s brain during pregnancy.

For example, we know only a handful of the hormones involved—out of hundreds scientists think may exist—and very little about how they might impact the brain. This gap in our understanding is one of the reasons we don’t have great treatments for pregnancy-related maladies, whether it’s extreme nausea, or anxiety and depression.

Closing this gap is the ...

Here’s a question for you that may at first seem trivial, but is actually profound: Why do our minds drift? 

If you have ever dabbled in mindfulness or meditation, you know this mind wandering has an almost gravitational pull. In fact, researchers now think we spend as much as 50 percent of our waking time in this state, which cognitive scientists have dubbed the brain’s “default mode.”

Today’s guest is Vinod Menon. He’s a giant in t...

For decades, Alzheimer's research has focused on clearing amyloid plaques from the brain. But new drugs that successfully remove plaques have proven clinically "underwhelming", leaving the field searching for alternative approaches.

Stanford neurologist Katrin Andreasson has spent twenty years pursuing a different path—investigating how aging triggers an energy crisis in the brain's immune and support cells. Her ...

The AI revolution of the past few years is built on brain-inspired neural network models originally developed to study our own minds. The question is, what should we make of the fact that our own rich mental lives are built on the same foundations as the seemingly soulless chat-bots we now interact with on a daily basis?

Our guest this week is Stanford cognitive scientist Jay McClelland, who has been a leading figure in this field s...

Imagine what it’s like to lose your ability to speak. You know what you want to say, but the connection between your brain and the muscles that form words is no longer functioning. For people with conditions like ALS, or who experience a severe stroke, this is a devastating reality. 

Today's guest is Erin Kunz, a postdoctoral researcher in the Neural Prosthetics Translational Laboratory at Stanford, who is part of a global comm...

Neuroscientists have spent the past few decades tracing the network of brain systems—some deep and emotional, and others more analytical and deliberate— that work together as we make tough choices like where to invest our money as well as more everyday decisions like which videos to watch online—or, for that matter, which podcast to listen to.

You can imagine that the ability to listen in on the brain systems that guide our choices ...

We are more isolated from one another than ever before — by our technology, by our political divides, and most of all, by our choices. 

This week on the show, we talk with neuroscientist Ben Rein about why this social isolation is terrible for our health — implicated in not only rising rates of mental illness, but also heart disease, dementia and more.

We discuss Ben's new book, "Why Brains Need Friends: The Neuroscience of...

Before the written word — and possibly even before speech — humans have communicated through drawing. From crude scratches in the dirt or on cave walls to the arcane symbology of the laboratory whiteboard, our instinct for conveying our thoughts visually is pretty extraordinary. 

We see or understand something in the world, we build an idea in our mind of what we think we see, and then using our hand and the utensil we re-create it ...

Imagine if you couldn't distinguish between dreams and reality. If you couldn't tell whether what you were seeing or hearing was really there in front of you. What if you discovered you couldn't trust your own perceptions? 

Psychosis is something three out of every a hundred people will experience at some point in their lifetimes. But what exactly is it, and is it something people can learn to live with?

Today we'...

Most of us can agree: music is awesome. Regardless of which songs speak to you, music probably plays an important role in your life. The question is, what makes music so powerful? Why does a particular combination of sounds and rhythms grab us and affect us in the way that it does? And is it true that music can help heal patients with Alzheimer's, Parkinson's, PTSD, chronic pain, and more? 

To help us understand what we&ap...

In this episode, we explore the fascinating neuroscience behind how children learn to read with Bruce McCandliss, director of the Stanford Educational Neuroscience Initiative.

Key topics include:
• How our brains "recycle" visual and language circuits to create reading expertise
• The crucial threshold when reading shifts from effortful to automatic
• Why some children struggle more than others to develop readi...

Recognizing a familiar voice is one of the brain’s earliest social feats. But what are the brain circuits that let a newborn pick out mom in a crowded nursery? How do they change as kids turn toward friends and the wider world? And what are we learning about why this instinct fails to develop in the autistic brain?

This week, host Nicholas Weiler joins Stanford neuroscientist Dan Abrams on the quest to understand the neural “hub” th...

In this special crossover episode, we’re doing something a little different. From Our Neurons to Yours host Nicholas joins producer Michael Osborne to co-host his podcast Famous and Gravy for a lively conversation about the extraordinary life and mind of Stephen Hawking.

Hawking, one of the most renowned scientists of our time, lived with ALS for more than 50 years—defying medical expectations while also reshaping how we understand ...