Informonster Podcast

In this episode, Charlie Harp discusses why healthcare’s long-standing definition of “good enough” data no longer works in a world increasingly driven by interoperability, analytics, and AI.  Drawing from a recent presentation at the AMIA Amplify Conference 2026, Charlie breaks down the growing gap between the way healthcare data was originally designed to function and the way organizations are now trying to ...

 In this episode, Charlie sits down with Clinical Architecture's VP of Marketing, Jaime Lira, to unpack the whirlwind of the spring healthcare conference season. 

From ViVE and HIMSS to the CMS Quality Conference and the ASTP Annual Meeting, they cover what made this year's circuit stand out. Including why booth conversations felt deeper than ever, how different conferences serve completely different purposes, and what it ...

In Episode 50 of the Informonster Podcast, Charlie Harp sits down with Rachel Dunscombe, CEO of HL7 International, to talk about her journey through healthcare, digital transformation, and standards development.

Rachel shares the experiences that shaped her perspective on interoperability from leading digital initiatives within the NHS to now working at the center of standards development as CEO of HL7 International. Charlie and Rac...

In Episode 49 of the Informonster Podcast, Charlie Harp sits down with Gene Vestel, host of Out of the FHIR Podcast and founder of FHIR IQ.

Gene shares his journey from pharmacy analytics to leading FHIR initiatives and advising organizations on digital quality measurement. He and Charlie discuss how FHIR has evolved, where it delivers value, and where organizations still struggle to make exchanged data truly computable.

They also ex...

In Episode 48 of the Informonster Podcast, Charlie Harp is joined by Clinical Architecture’s UK team members Chris Gray and Alex Wren to explore how pharmacogenomics is moving from research into real-world clinical practice.

They dive into the Progress Project, a groundbreaking NHS initiative integrating genetic insights directly into clinical workflows to support safer, more personalized medication prescribing. From building ...

Healthcare access isn’t just about availability, it’s about data. In this episode of The Informonster Podcast, Charlie Harp sits down with Sarah Matt, MD, MBA, Health Technology Strategist, and author of The Borderless Healthcare Revolution, to explore how gaps in healthcare data continue to create barriers for patients, providers, and caregivers alike.

Dr. Matt shares insights from her career spanning clinical practice,...

In Episode 46 of the Informonster Podcast, Charlie Harp sits down with John D’Amore a leading voice in healthcare informatics, data standards, and interoperability.

From his early days in decision support to building and selling a data normalization company, John shares the experiences that shaped his career and the lessons he’s learned along the way. Together, Charlie and John dig into the evolution of interoperability,...

In Episode 45 of The Informonster Podcast, host Charlie Harp sits down with Ryan Howells, Principal at Leavitt Partners, to explore how collaboration, policy, and open standards are driving meaningful innovation in healthcare.

From the origins of the “Kill the Clipboard” initiative to the push for better data quality, Ryan shares how he and his team at Leavitt Partners are helping align government and industry leaders to...

In this episode of the Informonster Podcast, Charlie Harp is joined by Sarah DeSilvey, DNP, FNP-C, Co-founder and Director of Terminology for the Gravity Project, to discuss the evolution of data standards supporting social determinants of health (SDOH). Together, they explore how Gravity’s collaborative work within HL7 is helping define and standardize social care data to improve interoperability and care coordination.

Sarah ...

In this episode of the Informonster Podcast, Charlie Harp takes on a new kind of guest, ChatGPT, to explore the evolving role of artificial intelligence in healthcare. 

Together, they discuss how generative AI is shaping clinical workflows, where it adds value, and where human oversight remains essential.

The conversation covers topics from bias and data quality to the ethical guardrails needed to keep AI trustworthy. 

Charl...

In this episode of the Informonster Podcast, Charlie Harp sits down with healthcare IT rockstar Susan Clark for a candid conversation on the evolving world of healthcare policy. From the incentives that drive real change, to the challenges of interoperability, data quality, and patient identity, Susan shares her insights on what it takes to align policy with purpose.

Contact Clinical Architecture

• Tweet us at @ClinicalArch&n...

In this episode of the Informonster Podcast, Charlie Harp shares updates on the PIQI Framework and his experience at the HL7 Connectathon. He highlights progress across newly formed PIQI Alliance work groups, from claims and explanation of benefits to USCDI and quality measures like eCQMs and HEDIS. He also talks about new SAM developments, including detection and noise, and how community feedback is shaping PIQI’s evolution ...

Joerg Schwarz, Senior Director, Global Industry Strategy & Solutions, Healthcare Data & Interoperability of Infor joins Charlie Harp to explore the future of healthcare data. They unpack how AI is raising the bar for interoperability, why data quality can’t be an afterthought, and how the PIQI Alliance is bringing the industry together to drive meaningful change. From FHIR adoption to scalable innovation, Joerg shares...

In this episode of the Informonster Podcast, Clinical Architecture CEO Charlie Harp hands over the mic to our VP of Marketing, Jaime Lira, for a conversation about the evolution of the PIQI Framework. From its early beginnings as a taxonomy to its growing momentum across the industry, Charlie shares how PIQI has progressed, what’s coming next for the PIQI Alliance, and why standardizing patient data quality is more important ...

In this episode of The Informonster Podcast, Charlie Harp sits down with Michael Klotz, Founder and CEO of Velox, to explore how Velox is helping payers move toward smarter, more streamlined access to clinical data. They discuss how the Velox platform helps payers benchmark and improve data quality, and how shared standards and smart analytics are laying the groundwork for a more connected, responsive healthcare system. The episode...

Join Charlie Harp and Carol Macumber, EVP of Client Services at Clinical Architecture and Chair-Elect of the HL7 Board of Directors, as they unpack Carol's informatics work and her participation in HL7 through the years. From Carol's early days in informatics to leading initiatives like Gender Harmony, this episode takes a deep dive into the organization’s efforts to standardize healthcare data exchange.

They break down the ev...

In this episode of The Informonster Podcast, Charlie Harp talks with John A. Short, MBA, MS-IS, FEMA PDS, CPHIMS, Senior Executive Service (SES), Director, Federal & Commercial Interoperability of Federal Electronic Health Record Modernization (FEHRM) Office and John Rancourt, Deputy Director of ASTP’s Office of Standards, Certification, and Analysis. They discuss how the government, specifically the DoD and VA, are addre...

Charlie Harp is joined by Dr. Victor Lee, VP of Clinical Informatics at Clinical Architecture, to take a deep dive into how a methodical approach to value set creation and maintenance builds a solid foundation for downstream data analysis and improved healthcare outcomes. 

Dr. Lee introduces the 6 Cs Framework he developed to evaluate value set quality through dimensions like clarity, completeness, congruency, consisten...

In this episode of The Informonster Podcast, Charlie Harp and Clinical Architecture’s Vice President of Marketing, Jaime Lira, dive into the insights from the 2024 Data Quality Report.  

As they explore key trends from this year’s survey, the discussion highlights the increasing recognition of data quality's critical role in healthcare, impacting everything from population health to AI initiatives.  

Download th...