Amanda Knox Hosts | DOUBT: The Case of Lucy Letby

Amanda Knox Hosts | DOUBT: The Case of Lucy Letby

Lucy Letby – a young nurse – was found guilty of the murder of 7 premature babies, and the attempted murder of 7 more. A serial killer whose target was not just the youngest and most vulnerable, but those entrusted to her care. The UK legal system – amidst overwhelming public vitriol – threw the book at her. She is currently serving an unprecedented 15 whole-life sentences in prison. But, is everything as clear as it seems? Our host Amanda Knox – herself a victim of the court of public opinion – asks: if this case is really as open and shut as the world believes. Or if, there may be room for reasonable doubt as to Lucy Letby’s guilt…

Episodes

February 17, 2026 2 mins

It was a case that shocked the United Kingdom and the wider world. Lucy Letby, a young nurse, was found guilty of murdering premature babies. She was a serial killer whose target was not just the youngest, most vulnerable human beings alive, but also those entrusted to her care. But, is everything as clear as it seems? Host Amanda Knox asks if this case is really as open and shut as the world believes or if – in fact – ...

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Lucy Letby was branded Britain’s most prolific child serial killer. The headlines were instant and unanimous: guilty. Case closed...or maybe not. In the wake of her conviction, a quiet rebellion began among journalists, statisticians, and senior doctors who question whether the evidence told the full story.  Amanda Knox explores how one narrative took hold — and why another is now fighting to be heard.

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March 3, 2026 39 mins

The Countess of Chester Hospital sits on the edge of the historic town of Chester, concrete, functional, unremarkable. On the surface, it’s entirely typical. But what happened inside would become one of the most consequential events in modern British history. In this episode, we examine the setting at the centre of the Lucy Letby case — and the tragic events inside that set everythi...

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March 10, 2026 30 mins

Lucy Letby is arrested and police launch Operation Hummingbird. But from the very beginning, questions emerge about how the case was built and whether early assumptions shaped the direction of the investigation.

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March 17, 2026 36 mins

The trial of Lucy Letby begins. In Manchester Crown Court, prosecutors outline the case they say explains a series of unexplained collapses and deaths on a neonatal unit, setting the stage for one of the longest trials in modern British history.

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March 24, 2026 37 mins

Lucy Letby finally takes the stand. The defence presents its case, laying out its arguments as she answers for herself in court, but questions linger over what may have been left unsaid.

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March 31, 2026 33 mins

As Lucy Letby is handed her sentence, a growing group of controversial voices begins to question whether the case is as clear as it seemed. Driven in part by reporting from Rachel Aviv, these so-called “misfits and ghouls” raise uncomfortable doubts, despite the personal risk. 

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April 7, 2026 28 mins

At Lucy Letby’s retrial, the prosecution leans on a single, powerful eyewitness account, but cracks begin to appear in the story the jury is asked to believe. When a previously unseen email surfaces, it raises troubling questions about whether that testimony was ever as certain as it seemed.

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April 14, 2026 30 mins

A profession under pressure. A culture of blame. And from inside the hospital environment, a perspective on the case few have heard.

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April 21, 2026 42 mins

In court, one interpretation of the evidence helped secure a conviction. But as concerns about the case quietly grow, a panel of international experts comes together to re-examine the medical evidence from the ground up, uncovering details the jury never heard and raising serious questions about the verdict itself.

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April 28, 2026 44 mins

In theory, certainty follows evidence. But once it takes hold, in court and amongst the public, it can be difficult to challenge. For those caught inside it, the consequences extend far beyond the courtroom, leaving lasting marks on both individuals and the systems that judged them. And in Lucy Letby’s case, the question of what happens next remains open.

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May 5, 2026 38 mins

Before Lucy Letby, another nurse was convicted under eerily similar circumstances: Lucia de Berk. Convicted on statistical evidence that later unraveled, her case reveals how flawed numbers can shape and shatter a conviction. In this bonus episode, Professor Richard Gill explains how the numbers went wrong, and what it took to overturn a life sentence.

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May 12, 2026 26 mins

A watchdog body was created after a series of wrongful convictions shook public confidence in British justice, yet once the system decides someone is guilty, overturning that verdict can still become almost impossible.

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June 16, 2026 36 mins

Clare and Carl had their baby at the Countess of Chester hospital in 2016. They share their shocking experience of their time there while Lucy Letby was a nurse on the ward.

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June 23, 2026 36 mins

Lucy Letby's Barrister Mark McDonald and MP David Davis discuss the case and what's next legally and politically. 

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June 30, 2026 34 mins

Amanda travels to Chester to meet two NHS whistleblowers from the Countess. They share their challenging experiences of working in the hospital's mortuary and their subsequent treatment when they attempted to raise the alarm. Trigger Warning: Death and Dead Bodies

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