The Builders

The Builders

Whose imagination do you want to live in? In this new series, bestselling biographer Walter Isaacson sits down with the most consequential names in AI and tech to understand the futures they're racing to build. Elon Musk, Peter Thiel, Alex Karp, Fei-Fei Li, Dario and Daniela Amodei, and more open up about their ambitions, what frightens them, how they think about humanity, and what drives them to build so big and so fast. The conversations are intimate, charming, and sometimes chilling. But mostly, they're impossible to dismiss. Because whether or not you agree with them, it's their imagination we're all starting to live in. ABOUT THE HOST Walter Isaacson is the bestselling author of biographies of Elon Musk, Jennifer Doudna, Leonardo da Vinci, Steve Jobs, Benjamin Franklin, and Albert Einstein. He is a professor of history at Tulane University and previously served as CEO of the Aspen Institute, chair and CEO of CNN, and editor of Time. He was awarded the National Humanities Medal in 2023. IN THIS SEASON Elon Musk (Tesla, SpaceX, xAI) Peter Thiel (Founders Fund, PayPal, Palantir) Mustafa Suleyman (Microsoft AI, DeepMind) Dario Amodei and Daniela Amodei (Anthropic) and more!

Episodes

October 30, 2026 • 47 mins

Episodes three and four of The Builders with Walter Isaacson explore two poles of the AI safety debate through interviews with Daniela and Dario Amodei, co-founders of Anthropic, and Mustafa Suleyman, CEO of Microsoft AI.

Joining Kaleidoscope co-founders Oz Woloshyn and Mangesh Hattikudur to unpack these interviews are two journalists who have spent countless hours trying to understand what drives those leading the AI revoluti...

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As a co-founder of DeepMind, Mustafa Suleyman helped launch the modern AI race. Now, he’s challenging the way it’s being built. As CEO of Microsoft AI, Suleyman believes the technology needs to be harnessed to transform medicine, energy and education. But he also warns that believing in AI consciousness could pose a real threat to humanity.

Recorded live at the 92NY, Suleyman explains his disagreement with Anthropic, id...

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Dario and Daniela Amodei, the siblings behind Anthropic, left OpenAI to pursue a different, “more human” approach to the technology. Their promise is to put AI safety and ethics at the center of the tech race… but with an IPO around the corner, can those principles survive the pressure to win? 

Walter invites the co-founders to explain how they teach Claude right from wrong, what they’ve discovered abo...

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October 23, 2026 • 50 mins

Curious how those chronicling Elon Musk and Peter Thiel are feeling about their appearances on The Builders? There's an episode of TechStuff for that. 

Host Oz Woloshyn is joined by his Kaleidoscope co-founder Mangesh Hattikudur to talk about how The Builders with Walter Isaacson… and all the high-profile interviews featured in the podcast came together. Joining them to break down these rare conversatio...

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Peter Thiel has become one of the most mysterious and controversial figures in tech. He’s a visionary investor who recognizes transformative ideas before everyone else. But he’s also seen as a shadowy figure whose network has accumulated extraordinary influence across Silicon Valley, national security and politics– proven by his bets on people like Elon Musk, Alex Karp, Sam Altman, and even Vice-President JD Vance...

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Elon Musk has spent his career turning improbable ideas into companies that reshape the world. To some, the entrepreneur behind Tesla and SpaceX is an engineering genius whose ambitions have transformed electric cars and space travel. To others, his politics and extraordinary influence raise serious questions about the future he is building. Either way, the world’s first trillionaire is betting Tesla’s future on AI and ...

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As a teaser to our upcoming series The Builders-- which kicks off with an interview with Elon Musk, we're re-airing our critically acclaimed 2023 podcast On Musk, Walter Isaacson's behind-the-scenes telling of writing the Elon Musk biography.  We hope you enjoy it!

Which of Musk’s efforts will mark his legacy? Will it be Starship and his work bringing Americans back into orbit, or will it be X and his amplifications of t...

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As a teaser to our upcoming series The Builders-- which kicks off with an interview with Elon Musk, we're re-airing our critically acclaimed 2023 podcast On Musk, Walter Isaacson's behind-the-scenes telling of writing the Elon Musk biography.  We hope you enjoy it!

Be a storyteller, not a preacher. That was novelist Walker Percy’s legendary advice to a young Walter Isaacson. One he takes to heart in his work as a journal...

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October 15, 2026 • 43 mins

As a teaser to our upcoming series The Builders-- which kicks off with an interview with Elon Musk, we're re-airing our critically acclaimed 2023 podcast On Musk, Walter Isaacson's behind-the-scenes telling of writing the Elon Musk biography.  We hope you enjoy it!

What kind of titan of industry has a "giddy mode"? Or a "demon mode"? The two aspects of Musk’s personality are forces that drive his choices and behavior at ...

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October 14, 2026 • 32 mins

As a teaser to our upcoming series The Builders-- which kicks off with an interview with Elon Musk, we're re-airing our critically acclaimed 2023 podcast On Musk, Walter Isaacson's behind-the-scenes telling of writing the Elon Musk biography.  We hope you enjoy it!

Space travel, electric vehicles, future-powering batteries—the ability to push technology forward and to bring it into the world in a real way is without a d...

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October 6, 2026 • 2 mins

Whose imagination do you want to live in? In this new series, bestselling biographer Walter Isaacson sits down with the most consequential names in AI and tech to understand the futures they're racing to build. Elon Musk, Peter Thiel, Alex Karp, Fei-Fei Li, Dario and Daniela Amodei, and more open up about their ambitions, what frightens them, how they think about humanity, and what drives them to build so big and so fast. The conve...

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