Pick Your Poison

Pick Your Poison

Dr. JP shares her passion for poisons in this interactive show. Pick Your Poison is a fast-paced, interactive podcast about poisons and toxins, mischief and murder ranging from ancient history to pop culture. Your choices direct the diagnosis and treatment. Make the wrong choice and our patient won’t survive the podcast.

Episodes

August 11, 2026 27 mins

A routine medication turns catastrophic when a patient's brain loses its brakes. Why won't the seizures stop? What hidden diagnosis is everyone missing? And what life-saving antidote has to be given before it's too late? Join Dr. JP as you investigate a rapidly deteriorating patient while exploring emergency medicine, toxicology, and one of the most dramatic poisoning emergencies you'll ever encounter. Your patient is waiting. Your...

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A notorious green spirit served in a Belle Époque bar. A violent patient hallucinating and fighting invisible enemies. And a medical myth linked to some of history’s most famous artists.

Your patient. Your diagnosis. Your decision.

An interactive emergency medicine and toxicology case involving sudden psychosis, dangerous behavior, hallucinations, substance use, medical versus psychiatric causes, and the myths s...

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A harmless-looking plant gathered for a wilderness dinner. An ancient remedy for madness associated with Heracles. And a flower carrying the same kind of cardiac poison found in toxic toads.

Your patient. Your diagnosis. Your decision.

An interactive wilderness and emergency medicine case involving mistaken foraging, plant poisoning, vomiting, dangerous heart rhythms, persistent symptoms, and ancient Greek medicine.

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A normal conversation followed by unconsciousness within minutes. A drug abandoned as too dangerous for medicine but reborn on the illicit market. And prison contraband hidden on an apparently blank sheet of paper.

Your patient. Your diagnosis. Your decision.

An interactive emergency and forensic toxicology case involving highly potent synthetic-drug exposure, sudden respiratory depression, hidden prison contraband, overdose reversal...

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Want to know what toxin has been killing workers since Paleolithic times—and is hiding in modern kitchens? The ancient Romans called it a widow-maker… because husbands died so quickly, some women had as many as seven. 

Listen to find out! 
 

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An animal that poisons without biting or stinging. An infamous aphrodisiac behind centuries of terrible decisions. And a blistering substance used as a murder weapon.

Your patient. Your diagnosis. Your decision.

An interactive forensic toxicology case involving animal-derived exposure, severe skin and urinary-tract injury, internal burns, gastrointestinal symptoms, kidney damage, and a long history of malicious poisoning.

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A poison that can burst into flame in the emergency department. Vomit and stool dangerous enough to threaten the medical team. And a possible answer to the missing bones of Waterloo.

Your patient. Your diagnosis. Your decision.

An interactive emergency and hazardous-materials case involving spontaneous combustion, severe gastrointestinal injury, liver failure, patient decontamination, staff safety, and battlefield history.

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A candy flavor beloved around the world. An ancient treat found in King Tut’s tomb and rumored to make camels less thirsty. And an overdose that drives blood pressure up while throwing the heart out of rhythm.

Your patient. Your diagnosis. Your decision.

An interactive medical toxicology case involving candy and herbal-product exposure, severe hypertension, low potassium, muscle weakness, cardiac arrhythmias, and electrolyte tr...

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April 14, 2026 21 mins

Fire eaters who damage their lungs without being burned. Hot-tub users who develop a serious respiratory illness. And gasoline thieves poisoned by the way they steal it.

Your patient. Your diagnosis. Your decision.

An interactive pulmonary and emergency medicine case involving hydrocarbon aspiration, chemical pneumonitis, cough, low oxygen, secondary infection, and treatment that may not involve antibiotics.

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Today's episode is about a toxin so powerful that a little smeared on the tip of a blowgun arrow is enough to silence every muscle in your body, including your diaphragm, stopping your breathing. How did a poison like this become a commonly used drug in modern medicine? 

We'll also go inside a Siberian prison cell where one of the most high-profile political prisoners on the planet collapses and dies. Was this a state-sponsored...

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A fever that refuses to break with ordinary medicine. Muscles rigid enough to trap a conscious patient inside the body. And the diagnostic chaos caused by “a round white pill.”

Your patient. Your diagnosis. Your decision.

An interactive medication-safety case involving a severe drug reaction, hyperthermia, muscle rigidity, altered mental status, medication identification, supportive care, and competing diagnoses.

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A foraged mushroom served at a royal meal. A dinner said to have ended the House of Habsburg and changed Europe. And a plant extract investigated as an antidote to liver failure.

Your patient. Your diagnosis. Your decision.

An interactive wilderness and emergency medicine case involving mushroom foraging, delayed gastrointestinal symptoms, severe liver injury, transplant evaluation, and uncertain antidote evidence.

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A healthy infant who becomes too weak to cry or feed. A digestive system missing key protective bacteria and bile acids. And a lifesaving antidote produced with help from scientists—and horses.

Your patient. Your diagnosis. Your decision.

An interactive pediatric toxicology case involving foodborne or environmental spores, descending paralysis, poor feeding, respiratory failure, stool testing, and specialized antitoxin treatmen...

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January 28, 2026 21 mins

A locked room with no intruder. A dead person with no sign of trauma. And a volatile clue that vanishes before investigators arrive.

Your patient. Your diagnosis. Your decision.

An interactive forensic toxicology mystery involving enclosed-space exposure, sudden collapse, oxygen displacement, scene safety, postmortem uncertainty, and a substance that leaves little evidence behind.

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A natural poison that harms humans but leaves bees untouched. A rare honey valuable enough to risk lives harvesting it. And a sweet weapon used in conflicts between Russia and Ukraine.

Your patient. Your diagnosis. Your decision.

An interactive foodborne and wilderness medicine case involving contaminated honey, vomiting, low blood pressure, dangerously slow heart rate, cardiac monitoring, and ancient biological warfare.

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December 9, 2025 19 mins

An easy-to-buy drugstore product that can paralyze like a famous bacterial poison. An old-fashioned enema once used for brain injuries. And a treatment choice that turns constipation into a toxic emergency.

Your patient. Your diagnosis. Your decision.

An interactive medication and gastrointestinal toxicology case involving enema misuse, electrolyte disturbance, muscle weakness, respiratory failure, ECG changes, and urgent supportive ...

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A beer-related ingredient other than alcohol that can cause disease. A diagnosis defense attorneys may be especially fond of. And the reason every person has a measurable blood-alcohol level—even without drinking.

Your patient. Your diagnosis. Your decision.

An interactive gastrointestinal and forensic medicine case involving internal fermentation, altered mental status, disputed intoxication, microbiome changes, diagnostic tes...

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November 11, 2025 15 mins

A gas that has killed thieves entering treated homes. A pesticide potent enough to threaten entire families. And a fumigant with consequences for the ozone layer.

Your patient. Your diagnosis. Your decision.

An interactive environmental and occupational toxicology case involving home fumigation, nausea, seizures, heart and lung injury, responder safety, decontamination, and limited antidote options.

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Poisoning advice delivered by a chatbot. A drug toxicity whose name also means stale or unoriginal. And a naturally occurring substance concentrated in the Dead Sea.

Your patient. Your diagnosis. Your decision.

An interactive medication and digital-safety case involving dangerous self-treatment, neurologic changes, abnormal electrolytes, online misinformation, laboratory diagnosis, and supportive toxicology care.

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October 14, 2025 20 mins

A street drug nicknamed “rhino tranq.” An adulterant also used routinely in emergency and intensive care. And a withdrawal syndrome that can become life-threatening.

Your patient. Your diagnosis. Your decision.

An interactive addiction-medicine case involving contaminated street drugs, profound sedation, slow heart rate, high blood pressure, severe withdrawal, and uncertainty about the modern drug supply.

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