This Episode is based on a comprehensive review article on therapeutic antiaging strategies (presented by MDPI, Basel, Switzerland). It explores aging as a progressive physiological process characterized by nine specific hallmarks, which are significant risk factors for various diseases. The review discusses different antiaging approaches based on these hallmarks, drawing on in vitro and in vivo research experiments. Strategies covered include anti-inflammatory drugs, antioxidant activity, telomere reactivation, epigenetic drugs, activation of the proteolytic system, mitophagy activators, inhibition of mTOR and insulin/IGF-1 signaling, activation of AMPK and Sirtuin signaling, clearance of senescent cells, stem cell-based therapies, the role of the microbiome, and noncoding RNAs. Ultimately, the article aims to highlight methods for promoting healthy aging and potentially extending human lifespan.
After listening to our podcast, you might wish to take the next step in your health journey!
While this podcast provides valuable information, our sibling website, **UnwindAging.com**, offers the comprehensive resources you need to actively slow aging and boost your vitality. Find practical tools, science-backed strategies, and personalized support. We specialize in demystifying carefully selected scientific studies, focusing on effective natural solutions. Plus, our blog posts link directly to relevant, research-backed, and cost-effective supplement options to support your optimal health.
Don't just listen, take action!
Visit also our blog now to unlock your potential for a healthier, longer life.
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Boysober
Have you ever wondered what life might be like if you stopped worrying about being wanted, and focused on understanding what you actually want? That was the question Hope Woodard asked herself after a string of situationships inspired her to take a break from sex and dating. She went "boysober," a personal concept that sparked a global movement among women looking to prioritize themselves over men. Now, Hope is looking to expand the ways we explore our relationship to relationships. Taking a bold, unfiltered look into modern love, romance, and self-discovery, Boysober will dive into messy stories about dating, sex, love, friendship, and breaking generational patterns—all with humor, vulnerability, and a fresh perspective.
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com