MedInsights Unleashed

MedInsights Unleashed

The MedInsights Unleashed Podcast aims to break down complex clinical data to provide insights from cutting-edge developments into tangible benefits for physicians, patients, and caregivers around the globe. Zee Ramji and John Collins will engage with leading global healthcare specialists to bring the latest groundbreaking therapies to you. To learn more about Zee and John, go deeper into each episode and access additional resources, go to https://medinsightsunleashed.com

Episodes

August 28, 2025 46 mins

We are privileged to have Dr. Ari Rosenberg, MD, and Dr. Maha Elsebaie, MD, MSc, from the University of Chicago, join us to discuss groundbreaking research in neoadjuvant head and neck cancer treatment. This episode explores how circulating HPV DNA, measured through a simple blood test, is emerging as a powerful tool to guide therapy decisions, personalize treatment, and potentially reduce the need for aggressive surgery or radiati...

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Groundbreaking research presented at ASCO with Dr. Elinor Barsh, MD, and Dr. Jacob Keeling, MD, focuses on advances in immunotherapy for CTLA-4 resistant melanoma. This episode highlights the importance of recent progress, including the Phase I study of the antibody–drug conjugate ozuriftamab vedotin. Dr. Barsh and Dr. Keeling discuss new clinical trial data, evolving treatment pathways, and the significant reduction in mortality r...

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Dr. Sharlene Gill, MD, joins the MedInsights Unleashed podcast to discuss the Challenge Study's promising results on exercise in cancer care. Conducted over 17 years, the study revealed that colon cancer patients engaging in structured exercise post-treatment exhibited improved survival rates. The trial involved a comprehensive three-year program incorporating both in-person and virtual components, emphasizing physical activity alo...

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In this episode of MedInsights Unleashed, Dr. Ari Goldman, MD, FAAOS, and Lewis Collins, OPA-C, ATC, OTC, from the Northwell Health Orthopedic Trauma and Surgery Team, uncover the facts on knee replacements. The discussion kicks off with a detailed look at knee anatomy and the factors leading to knee replacements, such as arthritis and genetic predispositions. The episode delves into the importance of maintaining knee health throug...

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Professor Philip A. Philip, MD, PhD, FRCP, Professor of Medical Oncology at Wayne State University School of Medicine and the Henry Ford Cancer Institute, returns to the MedInsights Unleashed podcast discusses the intricate topic of neuroendocrine tumors(NETs), including their rarity, the non-aggressive nature of many cases, and their potential functional characteristics. Prof. Phillip clarifies common misconceptions, advisi...

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In this episode of MedInsights Unleashed, Dr. Kriti Dhamija, MD, a second-year resident in the Department of Internal Medicine at Allegheny Health Network, Pittsburgh, Pennsylvania, USA, challenges the misconceptions around palliative care, particularly in pancreatic cancer. She explains why palliative care should begin at diagnosis, not at the end of life, and how early referral can reduce ER visits, hospital stays, and ICU admiss...

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In a recent episode of MedInsights Unleashed, Dr. Danny Rischin, MD, medical oncologist/clinician researcher at the Peter MacCallum Cancer Centre and Professor, Sir Peter MacCallum Department of Oncology, University of Melbourne, discusses the groundbreaking C-POST study focused on cutaneous squamous cell cancer. By utilizing the immunotherapy drug, cemiplimab, the study achieves a 68% reduction in the risk of recurrence, mar...

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In this episode of MedInsights Unleashed, Professor Philip A. Philip, MD, PhD, FRCP, Professor of Medical Oncology at Wayne State University School of Medicine and the Henry Ford Cancer Institute, shares vital insights into one of the most challenging cancers to detect and treat—pancreatic cancer. He highlights the urgent need for early recognition of symptoms and the growing understanding of genetic risks, including BRCA mutations...

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In this hard-hitting episode of MedInsights Unleashed, we tackle the escalating crisis of drug-related medical emergencies with guest speaker Eric Prach, MAS, BPsych—an EMT and police officer on the frontlines. This episode uncovers the harsh realities of fentanyl-laced overdoses, the rise of synthetic additives like Xylazine, and the increasing concern over Kratom use among young individuals.

Eric provides critical insights into th...

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Episode Summary:

This is the second episode in our series on colorectal cancer. In this episode of MedInsights Unleashed, we sit down with Prof. Paulo Hoff, MD, PhD, from the University of São Paulo, Brazil, to discuss the latest developments in colorectal cancer treatment. With cases increasing, especially among younger adults, the conversation underscores the importance of early screening and detection. Prof. Hoff explains how tum...

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Osteoporosis is often viewed as a women’s disease, but in this episode of MedInsights Unleashed, Dr. Tom Forfa, MBBS, reveals why men are also at serious risk. A retired physician and osteoporosis educator from Queensland, Australia, Dr. Forfa shares his personal journey, from multiple fractures to a delayed diagnosis, highlighting the need for early screening and awareness.

This episode uncovers misconceptions, risk factors, and tr...

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In this latest episode of MedInsights Unleashed, we are delighted to welcome Dr. Paulo Hoff, MD, PhD, Professor of Clinical Oncology at the Department of Radiology and Oncology, University of São Paulo. Dr. Hoff discusses the rising incidence of colorectal cancer in younger populations, highlighting key risk factors including poor diet, sedentary lifestyle, and obesity. He emphasizes the critical importance of beginning regular scr...

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In this MedInsights Unleashed episode, Dr. Christine Simmons, MD, Associate Professor in the Faculty of Medicine at UBC (University of British Columbia) and specialist in breast cancer and sarcoma, provides an in-depth exploration of the breast cancer journey, focusing on diagnosis, staging, and cutting-edge treatments for triple-negative breast cancer. She discusses the critical role of subtype differentiation and personalized car...

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In this MedInsights Unleashed episode, Dr Christine Simmons MD, Associate Professor in the Faculty of Medicine at UBC (University of British Columbia) and specialist in breast cancer and sarcoma, discusses breast cancer awareness, emphasizing the importance of regular screenings for early detection—especially post-COVID-19, as screening rates have significantly dropped. Early detection leads to better outcomes and less aggressive t...

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Elen Baloyan, MD, Oncology Fellow at Yeolyan Hematology and Oncology Center in Yerevan, Armenia, shares her insightful journey in this MedInsights Unleashed podcast episode. She addresses the financial toxicity affecting both doctors and patients in Armenia, which often leads to treatment refusals and late diagnoses due to high costs. Despite government efforts to support cancer care, the financial burden remains significant. Elen ...

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In this episode of MedInsights Unleashed, Dr. Oliver Bathe MD FRCSC, Professor of Surgery and Oncology University, CEO Qualisure Diagnostics Inc. discusses his journey from surgical oncology to pioneering precision cancer care. He delves into the role of machine learning in analyzing vast genomic databases to personalize treatment and improve patient outcomes. Dr. Bathe shares personal insights, emphasizing the importance of tailor...

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In this MedInsights Unleashed episode, Dr. Ari Rosenberg from University Chicago Medical Center, delves into the complexities and advancements in the treatment of head and neck cancers. Despite the recurrence and resistance these cancers often develop, immunotherapy has marked a significant breakthrough, especially in releasing the immune system's brakes. Although its introduction in early-stage cancer remains elusive, ongoing tria...

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In this episode Professor Philippe Merle explains the interplay between chronic liver conditions and the development of HCC. The conversation highlights the significance of early diagnosis and consistent patient monitoring to catch the disease in its nascent stages. Professor Merle also discusses the evolving landscape of HCC treatments, including innovative therapies and the benefits of a multidisciplinary medical team in managing...

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In this episode of Med Insights Unleashed, hosts Zee and John welcome Michael Staehler MD Ph.D, Professor of Urology at the University of Munich and Head the Interdisciplinary Center for Renal Tumors at Ludwig-Maximilian University, Munich. to discuss renal cell carcinoma. He explains how patient selection and managing side effects, including sexual dysfunction, play critical roles in effective cancer treatment. The conversation al...

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In this episode, hosts Zahra and John welcome Dr. Ari Rosenberg from University Chicago Medical Center, to explore head and neck cancer, a disease affecting nearly 900,000 people annually worldwide. Dr. Rosenberg delves into the complexities of diagnosing and treating cancers in the head and neck region. The discussion highlights the significant role of HPV, particularly in oropharynx cancers, and the promising impact of HPV vaccin...

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