The Human Upgrade with Dave Asprey

If your hair is thinning, shedding, or simply not what it used to be—and nothing seems to work—this episode is for you. Because what if the story you’ve been told about balding… is wrong? 

For decades, hair loss has felt like fate: genetic, inevitable, untouchable. But science is catching up to something deeper—something root-level. What if the real culprit behind age-related hair loss is cellular dysfunction? And what...

What if you could rewrite the code of your personality—on command? Not just cope with anxiety, overthinking, or social exhaustion… but delete the traits holding you back and install better ones? 

This episode challenges everything you’ve been told about identity. Dave dives deep into the science of personality change to reveal why your habits, moods, triggers, and even sense of self aren’t fixe...

Your brain isn’t broken—it’s underpowered. 

Energy crashes, poor sleep, brain fog, and emotional reactivity don’t just happen. You’re running on low voltage, and your mind pays the price. 

In this episode, Dave sits down with Dr. Patrick Porter, founder of BrainTap, to reveal how to reprogram your brain using light, sound, and guided visualization—no substances, no side effects, no BS. 

Dr. Porter bre...

You think you’re helping your kid. You clear the path. You smooth the bumps. You make sure they never feel too sad, too bored, too uncomfortable. 

It feels like love. 

But what if it’s making them weak? 

In this episode, Dave Asprey sits down with bestselling author, TED speaker, and resilience expert Jennifer Cohen to reveal how today’s parenting norms are quietly producing the most anxio...

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging? 

In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one co...

For nearly a century, scientists believed we had discovered ALL of the essential fatty acids the human body needs. But what if they were wrong? 

Stephanie Venn-Watson, a veterinary epidemiologist and longevity researcher, joins Dave to reveal a groundbreaking discovery—a newly identified essential fatty acid, C15, that may hold the key to healthier aging and even longer lifespans. Originally uncovered in an un...

You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? 

In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biological chaos hijacking your mind—and how to fight back. From inflammation and gut dysbiosis to screen-induced disconnection and hidd...

You think, you feel, you are—but what if your consciousness isn’t just in your brain? What if reality itself is shaped by something beyond the physical? 

In this episode, Mark Gober—author, consciousness researcher, and former Silicon Valley banker—joins Dave Asprey to challenge everything you think you know about the mind, reality, and human potential. He explores groundbreaking research on near-death e...

You hold the door open. You say yes when you mean no. You put others first—always. It feels like the right thing to do… but is it costing you more than you realize? 

In this episode, Scott Barry Kaufman, Ph.D.—Columbia professor, psychologist, and author of Rise Above—joins Dave Asprey to expose the psychology of victim vs. empowerment mindsets. He reveals how toxic altruism, external validation, and emotional fragilit...

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Your Brain is Lying to You—Here’s How to Take Back Control 

Every day, your brain is running subconscious scripts—hidden mental loops that shape your decisions, habits, and even your self-worth. But what if those loops are sabotaging you? 

In this episode, Bizzie Gold, mind architect and creator of The Break Method, joins Dave Asprey to expose the self-deception patterns controlling your thoughts—and...

Is the Way You Speak Limiting How You Think?

For years, scientists debated how language shapes the brain, but new research reveals it goes far beyond communication. Some languages lack numbers, grammar, or even complex sentences—yet their speakers navigate reality in ways that defy expectations.

In this mind-bending episode, linguist Daniel Everett, known for challenging Noam Chomsky’s theories, shares how his time with the ...

For decades, we’ve been told that our DNA is a fixed blueprint—an unchangeable code that dictates our health and lifespan. But what if that’s only half the story? 

Sharon Hausman-Cohen, a physician, researcher, and genomics expert at IntellxxDNA, joins Dave to reveal the cutting-edge science of genetic optimization—how understanding your DNA can unlock longer life, better brain function, and even protection f...

For years, we’ve been told that willpower and repetition are the keys to forming habits. But the truth is, habits don’t stick because of repetition—they stick because of emotion! 

In this all-time classic episode, Dave brings together two of the world’s top habit experts—BJ Fogg, PhD, and James Clear—to break down the real science of behavior change. BJ, the Stanford researcher behind Tiny Habits, explains wh...

In this first-ever AMA episode, Dave tackles your biggest biohacking questions—straight from The Upgrade Collective! From optimizing brain power to pushing the limits of cold therapy, this episode is packed with cutting-edge hacks to supercharge your body and mind. If you’d like to have your questions answered on the next AMA, click the link below for details on The Upgrade Collective membership, and get all sort...

Can You Mimic Fasting—Without Actually Fasting? 

Chris Rhodes, a biochemist and longevity researcher, joins Dave to reveal a groundbreaking fasting mimetic that could revolutionize how we approach aging, metabolism, and health. 

Fasting is one of the most powerful tools for longevity, but what if you could achieve the same benefits without hunger, energy crashes, or social sacrifices? Scientists have iden...