GasGasGas - Primary FRCA ’fun’

GasGasGas - Primary FRCA ’fun’

The Primary FRCA Podcast This will fit into a corner of your day, delivering a well explained concept critical to the knowledge required to pass the FRCA Primary Exam! This is relevant to anyone in the world interested in these pharmacological, physiological, clinical, physical and chemical concepts, naturally it is flavoured towards UK practice. Episodes will be (mostly) succinct, conceptually specific, and exam material focussed. Notes on gasgasgas.uk All content is my personal opinion, not medical advice and is never a substitute for formal education / training

Episodes

June 9, 2025 27 mins

Remifentanil is an anaesthetist’s dream: ultra-short acting, reliably titratable, and deeply potent. This episode takes a dual-pronged approach—covering both the FRCA-relevant pharmacology of remifentanil and introducing the Minto target-controlled infusion (TCI) model. 

Show notes at:

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In this explainer episode of GasGasGas, James delves into the joyful complexities of neuraxial opiate pharmacology. Why do we bother putting opiates into this space at all? What governs their journey, how do they behave once administered, and what clinical pearls can be drawn from their behaviour? This episode follows the journey of a single opioid molecule through the fatty labyrinth of the epidural space, across barriers, and int...

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In this episode of Gas, Gas, Gas, we dive deep into the pharmacology of diamorphine — also known by its more notorious street name, heroin. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applications, pharmacokinetics, pharmacodynamics, and side effect profile. The episode is structured to support FRCA Primary revision with an irrelevant clinical anecdote (...

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Episode Description: In this episode of GasGasGas, we a plunge into the pharmacology of oxycodone, a potent semi-synthetic opioid analgesic widely used in perioperative and chronic pain settings. Aimed at FRCA Primary candidates and anaesthetic trainees, this episode explores oxycodone's mechanism of action, pharmacokinetics, and pharmacodynamics, as well as its clinical indications, side effect profile, and relevance in anaesthesi...

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In this episode of the GasGasGas Primary FRCA podcast, we explore methadone—its pharmacology (pharmacodynamics and pharmacokinetics), diverse receptor activity, and its clinical uses.

While traditionally associated with managing opioid dependency, methadone’s unique pharmacodynamics and potential utility may have been overlooked given its other uses…

 

Show notes at: https://gasgasgas.uk/episode-24-methadone-for-the-frca-primary/

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This episode takes a dive into the detailed pharmacology of Tramadol focussing on the content to understand for the FRCA Primary exam. We explore its unique multi mechanism analgesic action, pharmacokinetics, clinical uses, and key points.

#Tramadol #Pharmacology #FRCAprep #Opioids #MultimodalAnalgesia #GasGasGasPodcast

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In this episode of GasGasGas, we explore Alfentanil, a short-acting μ-opioid receptor agonist pivotal for anaesthetic practice. Discovered in 1976 by Janssen Pharmaceuticals, Alfentanil remains a super handy agent, especially for (modified) rapid-sequence inductions and acute pain management.

 

Show notes at https://gasgasgas.uk/alfentanil-for-the-frca-primary/ 

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Welcome back to Gas, Gas, Gas—the podcast that breaks complex anaesthesia concepts into digestible, high-yield episodes. Today, we’re doing a deep dive into the TIVA Models for Propofol particularly the: Marsh, Schneider, and Eleveld TCI models.

This isn’t just academic—understanding the underpinnings of these models means you can dose more precisely, tailor your anaesthetic plan to the patient in front of you, and avoid the classi...

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In this VivaCast episode, we simulate a comprehensive FRCA Primary physiology viva covering three key topics: physiological response to acute blood loss, nerve conduction and classification, and acid-base balance including pH regulation and anion gap interpretation.

 

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Welcome to a special interview edition of GasGasGas – the podcast that explores anaesthetic life in all its glorious detail, venturing out into its terrifying, and deeply human dimensions.

I want those thinking about anaesthetics to gain insight, and I want everyone else Post IAC to remember the IAC experience and focus on what we can do to make IAC even better! Today, host James sits down with James, a CT2 ACCS anaesthetic traine...

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In this VivaCast episode, we present a complex clinical scenario involving an intravenous drug user (IVDU) presenting with an infected pseudoaneurysm.

Tom grapples with the challenges of these high BBV risk cases and managed local anaesthetic toxicity as it all goes terribly pear shaped!

Show Notes Here!

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In this episode of GasGasGas, we dive into the essential principles of pharmacokinetics, focusing on how drugs are processed by the body. We also explore the mechanisms and clinical implications of hypoglycaemic medications and discuss the fundamentals of clinical trials. Whether you're a medical professional or an interested listener, this discussion is packed with keywords, critical insights and the lingo needed to sound sharp in...

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This VivaCast episode covers essential FRCA Primary knowledge areas, focusing on ultrasound use and physics, cardiac output monitoring techniques, and the principles and safety considerations of diathermy in anaesthesia.

Designed to simulate the viva experience, this episode prepares candidates with model answers and key concepts likely to appear in the examinations.

Don't forget all the other VivaCast episodes! Shownotes HERE!

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Tom's exam inches ever closer to reality, here he gets caught out on Droperidol, nails the Journey a Propofol Bolus Takes and handles Anti-Microbial Surgical Prophylaxis.

Show-notes on gasgasgas.uk

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March 5, 2025 26 mins

Tom and James wade through Liver physiology, debrief afterwards when we try and devise a way to talk about this functions without listing out something written on our arms!

 

Check out the show-notes at gasgasgas.uk

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Classifying Hypoxia, Oxygen delivery and taking oxy-haemoglobin Sat Curves

 

Tom gets quizzed on what defines hypoxia, how oxygen is delivered to tissues and how the oxyhemoglobin disassociation curve behaves.

 

Shownotes on gasgasgas.uk

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Dr Gas Lurks on: 

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Website: www.gasgasgas.uk

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Tom talks cardiac physiology, exploring blood pressure, Hagen–Poiseuille law, and coronary blood flow, finishing up with a brief chat of the cardiac cycle.

There is a debrief and extra detailing at the end in very quick fire ‘words that convey you know what you’re on about’ sot of standing.

Show notes here!

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This viva cast takes Tom on an epic battle, sundering his way through the VIE, crossing the Wheatstone Bridge, looking around corners with Fibre Optics and finally zapping everyone with Lasers.

Show notes @ gasgasgas.uk

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Dr Gas Lurks on: 

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Website: www.gasgasgas.uk

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Tom experiences some catecholamine release of his own in this episode as he talks serpiginous GPCRs, Adenyl cyclase, PKA and comparing local anaesthetics, and getting tied up (like we all do) with the clinically pointless, but delightfully examinable Vaughan-Williams Anti-arrythmic classes!

We Debrief and break into some of the questions as we go.

As always the show notes are on the website!

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Tom dives into the critical details of how oxygen makes it to the mitochondria, tells me of this concept called shunt and then gets thoroughly beaten to shreds by the Valsalva manoeuvre - a tactical doozy that gets rolled out because it is a baffling set of steps.

  • Alveolar Gas Equation
  • Shunt
  • Hypoxic Pulmonary Vasoconstriction
  • Oxygen concentration Sensing of Plasma
  • And the Valsalva Manoeuvre.

We Debrief and break into som...

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