Future Science Group

Future Science Group

Podcast by Taylor & Francis Group

Episodes

Unveiling bioanalytical datasets for the successful development of ADCs

March 31, 2025 • 19 mins
Unveiling bioanalytical datasets for the successful development of ADCs
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Bridging science and safety: exploring toxicology studies and regulatory requirements

March 27, 2025 • 10 mins
Bridging science and safety: exploring toxicology studies and regulatory requirements
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Cell therapies for autoimmune diseases: a podcast with Lindsay Davies

February 19, 2025 • 13 mins
This International Women’s Day, we’re joined by Lindsay Davies, Chief Scientific Officer at NextCell Pharma (Stockholm, Sweden), to discuss the evolving role of cell therapies in treating autoimmune diseases. In this podcast, Davies breaks down the science behind NextCell’s mesenchymal stromal cell therapy for type 1 diabetes and explores how these cells could be applied to other autoimmune conditions. She emphasizes the importanc...
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The use of GenAI in bioanalysis: an interview with Priyata Kalra

February 6, 2025 • 28 mins
During the American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 2024 conference, Bioanalysis Zone caught up with industry experts across numerous disciplines to discuss their involvement with AAPS and their research. In this interview, we spoke to Priyata Kalra about her talk on the use of GenAI within biomedicine.
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The need for HRMS for quantitation of ADCs vs. QQQ: an interview with Megan Cooley

January 9, 2025 • 21 mins
In this episode, we sit down with Megan Cooley, Associate Director of Bioanalytical Services at ICON (KS, USA), to explore the cutting-edge world of antibody-drug conjugate (ADC) quantitation using high-resolution mass spectrometry (HRMS). Megan delves into the capabilities of Triple Quadrupole and Time-of-Flight mass spectrometry, offering her expert insights into whether HRMS is essential for ADC PK studies. We also tackle the ch...
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How can medical device regulation catch up with innovation?

December 16, 2024 • 12 mins
In this interview, we discuss the potential of AI in increasing healthcare system efficiency, how medical devices are making procedures less invasive and what those working in the field of medical devices can do to help regulation catch up with innovation.
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The new frontier: assessing efficacy and safety of CGTs using biomarkers

September 27, 2024 • 24 mins
In the sixth episode of The new frontier podcast, we're joined by Catherine Vrentas, Life Sciences Lead at Booz Allen Hamilton (VA, USA). Cathy explains how biomarkers can be used to predict the therapeutic outcome and efficacy of CGTs and the biomarkers in particular that have shown strong predictive value. We delve into the common challenges of working with biomarkers in CGTs and how biomarker kits can be adapted for CGT work.
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Carlon Fitzpatrick AI Summit

September 11, 2024 • 3 mins
Carlon Fitzpatrick AI Summit by Taylor & Francis Group
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Challenges and solutions in monitoring assay performance for vaccine development

July 31, 2024 • 18 mins
Challenges and solutions in monitoring assay performance for vaccine development: an interview with Atul Chaudhari
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ADA detection and characterization for immunogenicity testing: insights from ICON's Lindsay Denhoff

July 9, 2024 • 11 mins
We caught up with Principal Scientist Lindsay Denhoff (ICON; Dublin, Ireland) to discuss immunogenicity considerations for therapeutic proteins and the current analytical methodologies for detecting and characterizing anti-drug antibodies (ADAs). Lindsay shares some industry best practices for achieving high-quality ADA assays, as well as some of the advantages and limitations of singlicate ADA analysis compared with alternative te...
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Tech Blast | Epitope binning

May 16, 2024 • 19 mins
In this Tech Blast episode supported by Sartorius (Göttingen, Germany), we speak with David Apiyo – Manager of Applications Development at Sartorius (MN, USA) – about epitope binning, why it's performed and the best ways to conduct it. Plus, learn more about Sartorius' biolayer interferometry platforms and their application in epitope binning.
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Using the Gyrolab® platform for oligo quantification: an interview with John Chappell

April 30, 2024 • 6 mins
In this interview, we spoke to John Chappell, Senior Global Scientific Support Manager at Gyros Protein Technologies (Uppsala, Sweden) about his experience working with the Gyrolab platform for oligonucleotide assays. John discusses the advantages of using Gyrolab for oligo quantification in biological fluids and shares his thoughts on the next steps for these assays.
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The new frontier: qPCR vs ddPCR for cell and gene therapies

April 24, 2024 • 15 mins
In the fifth episode of The New Frontier podcast, we're joined by Paul Byrne, Senior Director of Genomics from ProtaGene (MA, USA). Paul describes his experience working with qPCR vs digital and digital droplet PCR assays and advises on their pros and cons, as well as when it's best to use each. We discuss how these assays can be optimized for cell and gene therapy targets and get a peek into the tips and tricks he's picked up over...
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The new frontier: using LC–MS/MS for quantitative assays to support gene therapies

March 26, 2024 • 13 mins
In this episode of The New Frontier podcast, we're joined by Daniel Schulz-Jander, Senior Director of Mass spectrometry Bioanalysis at QPS Netherlands (Groningen). Daniel explains how he uses immune-precipitation and immunoaffinity LC–MS techniques for his work relating to macromolecular pharmaceuticals like gene therapies, as well as their benefits and challenges. Daniel also covers bottom-up, middle-down and top-down approaches a...
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Breaking down barriers for women in tech: an interview with Tina Marshall

March 7, 2024 • 16 mins
Breaking down barriers for women in tech: an interview with Tina Marshall by Taylor & Francis Group
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Uncovering the link between cancer disparities and climate change

February 21, 2024 • 14 mins
What disparities exist in cancer screening and how does this impact patient outcomes? Listen to our latest podcast episode with Kilan Ashad-Bishop (American Cancer Society) to find out about the intersection between science, health, and society.
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AI-driven early disease detection: an interview with Jim Kean

February 16, 2024 • 28 mins
AI-driven early disease detection: an interview with Jim Kean by Taylor & Francis Group
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The new frontier: immunogenicity testing for cell and gene therapies with Johanna Mora

February 13, 2024 • 11 mins
In this episode, we spoke to Senior Director Johanna Mora about her experience with immunogenicity testing for cell and gene therapies (CGTs) and how she prepared for the expansion of BMS's portfolio to include CGTs. We discuss the importance of having diverse teams with a broad range of experiences to solve complex problems, as well as the role of artificial intelligence in improving our efficiency and spotting patterns in the dat...
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The new frontier: regulatory implications for cell and gene therapies with Kimberley Buytaert-Hoefen

February 12, 2024 • 18 mins
In the first episode of this series, we spoke to Executive Director and Global Head of Regulatory Services Kimberley Buytaert-Hoefen about her experience with cell and gene therapy (CGT) approvals and the barriers to getting these important therapeutics to the patient. Kim advises early regulatory interaction and collaboration to improve the success rate of applications and emphasizes the importance of global harmonization of regul...
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AI and the UK Biobank: an interview with Mahesh Pancholi

November 20, 2023 • 9 mins
AI and the UK Biobank: an interview with Mahesh Pancholi
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