Rumor vs Truth - Evidence‑Based Mythbusting for Healthcare Professionals

Rumor vs Truth - Evidence‑Based Mythbusting for Healthcare Professionals

Your trusted source for facts... where we dissect the evidence behind risky rumors and reveal clinical truths. This podcast series from TRC Healthcare, the team behind Pharmacist’s Letter, Pharmacy Technician’s Letter, and Prescriber Insights products, is designed to help pharmacists, pharmacy technicians, prescribers, and even patients navigate some of the claims they might see about medication therapy. Find the video version of this show on YouTube: https://www.youtube.com/@trc.healthcare TRC Healthcare offers CE credit for this podcast for subscribers at our platinum level or higher. Log in to your Pharmacist’s Letter, Pharmacy Technician’s Letter, or Prescriber Insights account and look for the title of this podcast in the list of available CE courses.

Episodes

September 15, 2026 • 31 mins

Generic drugs save money, but do they lower the bar? 

From what "bioequivalent" really requires to why an authorized generic can look just like the brand name, a lot of what gets assumed about generic drugs hasn't caught up with how tightly this corner of pharmacy is actually regulated. 

In this episode, Don and Steve pick apart the claims pharmacists hear most about generic drugs.

  • 🔬 Do generics really get held to a low...
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Naloxone and nalmefene are reaching more hands than ever—through bystander programs, pharmacy dispensing protocols, and over-the-counter sales. But as access expands, one question keeps coming up:

Does easier access to naloxone or nalmefene actually make opioid misuse worse?

In this BONUS mailbag episode of Rumor vs Truth, we answer a listener question about whether increasing naloxone and nalmefene access encourages opioid mis...

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August 18, 2026 • 24 mins

Opioid Rules of Thumb Are Sticky—Even When the Evidence Moves On. 

From how quickly dependence risk starts to whether the newest non-opioid really replaces an opioid, a lot of advice is still running on assumptions learned years ago. 

In this episode, Don and Steve separate opioid fact from folklore by challenging long-held assumptions with the latest evidence.   

  • 💊 How fast can dependence risk start aft...
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Can polyethylene glycol (PEG 3350, Miralax) affect the absorption of other medications?

In this BONUS mailbag episode of Rumor vs Truth, we answer a listener question about whether polyethylene glycol (PEG 3350) should be separated from other medications and, if so, by how long. Hosts Don Weinberger, PharmD and Steve Small, PharmD break down what the evidence actually shows about laxatives, intestinal transit time, a...

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July 21, 2026 • 27 mins

The Constipation Conversation Has Been Backed Up for Years.

From fears about laxative dependence to questions about pediatric safety, some laxative myths are still stuck in the system… despite growing evidence to the contrary.

In this episode, Don and Steve tackle some of the most common claims healthcare professionals hear about constipation treatment—and explore what the research really says. 

  • 💩 Why does docus...
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Ivermectin continues to come up in patient conversations—and not just for adults.

Can ivermectin now be used safely in all kids after the recent KIDs List update?

In this BONUS mailbag episode of Rumor vs Truth, we answer a listener question about ivermectin use in kids. Hosts Don Weinberger, PharmD and Steve Small, PharmD break down what actually changed with ivermectin in the 2025 update to the KIDs List&mdash...

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June 16, 2026 • 27 mins

Ivermectin Is Back in the Conversation—But What Should Healthcare Teams Know?

From expanded OTC access in some states to persistent online claims, ivermectin is once again popping up in patient conversations—and bringing plenty of confusion with it.

In this episode, Don and Steve dig into what’s driving the buzz and what the evidence actually shows across a surprisingly wide range of uses. From viral misinformation ...

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Gabapentin is showing up more often in veterinary care —but that raises an important question:

Is gabapentin toxic in animals?

In this BONUS mailbag episode of Rumor vs Truth, we answer a listener question about gabapentin use in pets. Hosts Don Weinberger, PharmD and Steve Small, PharmD dig into what’s really behind concerns about toxicity—and bring in veterinary toxicology expert Dr. Tina Wismer to...

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May 19, 2026 • 28 mins

Gabapentin has become a go-to option across a wide range of clinical scenarios—but how well does it actually hold up under closer scrutiny?

In this episode, Don Weinberger and Steve Small take a closer look at how gabapentin performs in real-world use—and where expectations may not match the data.

  • 🧠Does gabapentin meaningfully improve neuropathic pain outcomes—or are we overestimating its impact in everyday pra...
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Shorter antibiotic courses are becoming the norm—but that raises an important question we hear all the time:

Can patients stop antibiotics early once they start feeling better?

In this BONUS mailbag episode of Rumor vs Truth, we step outside our regular format to answer a single listener question submitted through our fan mail audio line. Hosts Don Weinberger, PharmD and Steve Small, PharmD revisit antimic...

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April 21, 2026 • 27 mins

Antimicrobial stewardship is everywhere—but best approaches are still debated.

In this episode, Don and Steve separate fact from fiction around antimicrobial stewardship - taking a closer look at how antibiotics are used in everyday practice—and where common beliefs may fall short.

  • 🦠 Does antimicrobial stewardship actually reduce antibiotic resistance?
  • ⏱️ Are shorter outpatient antibiotic courses—like 5 ...
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March 17, 2026 • 37 mins

AI is fast.
AI is fluent.
AI is confident.

But is it clinically trustworthy?

🤖 AI can generate answers in seconds.
But good healthcare decisions require more than speed.

As AI tools become more accessible across healthcare, the line between assistance and authority is starting to blur.

Don and Steve put artificial intelligence under the microscope—cutting through hype to examine how AI is actually performing in healthc...

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February 17, 2026 • 32 mins

Hair today… gone tomorrow? Don and Steve are combing through the claims to find out what really works. In this episode, they separate fact from fiction about hair loss treatments, tackling everything from minoxidil and finasteride to natural remedies and trending techniques.

💊Does oral minoxidil really outperform topical versions?
🧴Is topical finasteride genuinely a safer workaround, or do the same systemic side effects ...

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January 20, 2026 • 27 mins

Hot flashes or cool facts… are menopause and hormone replacement therapy (HRT) in the middle of the rumors? In this episode, Don and Steve turn up the heat on common claims about estrogen therapy and menopause management. Joined by guest expert Sara Klockars, PharmD, BCPS, they separate fact from fiction and share practical tips for clinicians.

🔥 Is HRT the go-to for every patient with hot flashes?
💊 Are bioidentical hor...

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December 16, 2025 • 27 mins

Are GLP-1 side effects food for thought or just food for rumors? In this episode, Don and Steve dig into the evidence behind the most talked-about risks of GLP-1 agonists, separating clinical truth from rumors and headlines.

🦱 Are these meds thinning waistlines—and hairlines?
🚹 Do GLP-1s cause erectile dysfunction—or could they actually help?
🛑Is holding GLP-1s before surgery a must, or just medical myth?

Our cli...

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November 18, 2025 • 31 mins

Is your favorite cold fix fact—or folklore? In this episode, hosts Don and Steve team up with special guest Jeff Langford, PharmD, from TRC’s NatMed team, to bust the biggest myths about natural remedies for cold and flu. Together, they dig into the roots of popular remedies—from pharmacy shelves to grandma’s kitchen—to uncover what’s backed by evidence.

🍯 Is honey for cough a sweet solution or j...

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We loved our conversation with Dr. Jayson Chalmers, DDS so much that we’re sharing the full, never‑before‑heard interview. It goes deeper than our last episode “Dental Dilemmas” on the history of fluoridation, chemistry, dosing, safety signals, and what clinicians should actually recommend. 

** No CE credit for this bonus episode. (CE returns with our next regular episode on cold & flu.) **

What you’l...

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October 21, 2025 • 30 mins

In this episode, Don and Steve separate fact from fiction about meds and oral health.

💊 Could your favorite mouthwash be more “spirited” than you think?
😬 Can a key medication for opioid use disorder quietly sabotage your smile?
🦷 What really happens when you put aspirin on a toothache—relief, or regret? 

Ready to brush up on the facts and drill down to the truth? No need to sugarcoat it, our myth-bust...

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In this “Quick Verdicts” episode, hosts Don Weinberger and Steve Small separate fact from fiction about whether acetaminophen use during pregnancy increases the risk of neurologic disorders in kids.   

****** 

TRC Healthcare Editor Hosts:  

  • Stephen Small, PharmD, BCPS, BCPPS, BCCCP, CNSC  
  • Don Weinberger, PharmD, PMSP 

****** 

The clinical resources mentioned during the podcast are ...

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September 16, 2025 • 23 mins

In this episode, Don and Steve flex their clinical muscles and bust myths about testosterone replacement therapy (TRT) - from supplements to safety risks.

🐶 Can topical testosterone transfer to pets and kids?
💊 Are supplements like ginseng and vitamin D legit testosterone boosters?
❤️ Does testosterone increase cardiovascular risk?

Stick around as our pharmacist duo breaks down the evidence and shares insights on these hot-bu...

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