Injectable BPC-157 vs Oral BPC-157

BPC-157 (body protection complex) is a peptide consisting of 15 amino acids. It’s become popular in recent years for its potential therapeutic benefits, particularly in tissue repair and inflammation reduction. 

BPC-157 is derived from a protein found in the human stomach. It promotes healing in a variety of health conditions, from muscle and tendon injuries to gut health and brain fog. 

BPC-157 is available as an oral pill or an injection into the fatty tissue (subcutaneous injection).

In this podcast, we’ll discuss the differences between these two dosage forms and which may be better for you.

Injectable BPC-157

Absorption and Bioavailability 

Injectable BPC-157 can be injected subcutaneously (under the skin) or intramuscularly (into the muscle). Injections ensure that the peptide bypasses the digestive system, allowing for direct entry into the bloodstream. As a result, the peptide's bioavailability is significantly higher with injections. Bioavailability refers to the proportion of a medication/peptide that enters the circulation and is able to have an active effect.

Effectiveness

Injectable BPC-157 is often seen as a better choice for healing injuries like torn ligaments and tendons, muscle tears, and joint damage. Injections can be given close to the injury site, which might help it heal faster.

Dosage and Administration

The dosage for injectable BPC-157 typically ranges from 400 to 600 micrograms per day for up to 12 weeks, followed by a one-month break. The BPC-157 dose and length of treatment depend on the severity of the condition and the individual’s response. 

Remember: Using injectable medication requires careful handling. You need to keep everything clean to avoid infections and use the right technique to ensure the peptide's effectiveness. 

Pros and Cons

• Pros:

• High bioavailability and potency

• Direct application to target areas

• Faster onset of therapeutic effects

• Cons:

• Requires needles and sterile conditions

• Potential discomfort or pain at injection sites

• More complex administration compared to oral forms

Oral BPC-157

Absorption and Bioavailability

Oral BPC-157 is taken in capsule or tablet form and digested in the gastrointestinal tract before entering the bloodstream. This route of administration can result in lower bioavailability due to the peptide being broken down by digestive enzymes and stomach acid. However, many people who use oral BPC-157 argue that it still retains sufficient bioactivity to be effective, particularly for gastrointestinal conditions.

Effectiveness

Oral BPC-157 is often chosen for its convenience and potential benefits for digestive health. Since it directly interacts with the gastrointestinal lining, it may be more effective for treating issues such as inflammatory bowel disease (IBD), ulcers, and leaky gut syndrome. It also helps to restore the gut microbiome. While systemic effects (e.g., muscle or tendon healing) might be less pronounced compared to injections, oral administration still provides therapeutic benefits, albeit possibly at a slower rate.

Dosage and Administration

The dosage for oral BPC-157 generally ranges from 500 to 1000 micrograms per day, reflecting its lower bioavailability. The exact dosage can vary based on individual needs and the condition being treated. Oral BPC-157 is easy to administer, making it more user-friendly for those uncomfortable with injections.

Pros and Cons

• Pros:

• Easy and painless administrat