Age of Aging

Age of Aging

Welcome to the Age of Aging, a podcast about living well with an aging brain. The Age of Aging is a podcast released every other Tuesday, covering a wide range of stories in aging research. Co-hosted by Jake Johnson and Terrence Casey from the Penn Memory Center communications team, each episode they will explore what it means to age with independence and dignity in the modern world. You can expect to hear from the University of Pennsylvania’s world-class researchers, caregivers of those with cognitive difficulties, and everyday people who want to keep their brain as healthy as possible as they age. Supported by the Penn Memory Center, Penn FTD Center, Penn Institute on Aging, and Penn Alzheimer’s Disease Research Center.

Episodes

July 8, 2025 39 mins

Sex and intimacy can be difficult topics to navigate, especially for caregivers and their partners facing the challenges of a dementia diagnosis. These conversations are often avoided, yet the emotional toll of intimacy-related struggles can be profound, bringing feelings of grief, confusion, and isolation. The stigma surrounding sex and dementia only deepens this silence, making o...

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The U.S. healthcare system is changingespecially when it comes to caring for older adults. The COVID-19 pandemic revealed how vulnerable our aging population is, and how unprepared many parts of the system remain. Overstressed nursing homes, overworked ...

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June 10, 2025 40 mins

We often think of dementia as something that affects the oldest among us, and that’s often true; at the Penn Memory Center, the average age of diagnosis is between 70 and 75. In most of those cases, caregiving falls to a spouse, partner, or adult child. But what happens when dementia is diagnosed before the age of 65? 

In this episode of the A...

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The world is getting older—and that reality is what inspired this podcast. Thanks to advances in medicine, healthier lifestyles, and improved living conditions, people are living longer than ever. That’s a good thing. However, longer lives will also require a lot of change from both individuals and society. We will have to prepare now for something earlier...

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May 13, 2025 37 mins

No one wants to think about their death, let alone talk about it. But having a meaningful conversation with your loved ones about your final days is one of the most important things you can do for them and yourself. End of life is a logistically and emotionally challenging time, so making critical decisions before the process of dying can save you and those around you from further ...

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April 29, 2025 41 mins

At the Penn Memory Center, one of the most common questions we hear is: What can I do to keep my brain healthy as I age?  

We often reference diet and exercise as essential tools when it comes to maintaining a healthy brain. There’s another, often-overlooked way to boost brain health, fight depression, and support cognitive resilience. It’s not a pill. It’...

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April 15, 2025 39 mins

In dementia care and research, it’s widely accepted that people living with advanced dementia often lose the ability to connect and communicate as they once did. However, one phenomenon has been the exception to the rule. “Paradoxical lucidity” is a term used to describe brief moments in which individuals with severe dementia suddenly regain clarity, communicate, and reconnect in w...

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March 25, 2025 10 mins

What does spring smell like?  

What do you think is a beautiful sound?  

If those questions made you pause for a second and reflect, that’s exactly the point. These are examples of “beautiful questions,” open-ended prompts designed to push you beyond your everyday thinking and invite you to look at the world a little ...

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January 21, 2025 36 mins

Welcome to a special bonus episode of the Age of Aging! As we bring in the New Year, we're taking a moment to reflect on the key milestones in dementia research and clinical care from 2024 and share our excitement for what's ahead in 2025. Today’s episode features a conversation between three distinguished leaders in dementia research and clinical care at ...

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December 10, 2024 43 mins

It’s the season 2 finale of the Age of Aging! To celebrate, we welcomed back guests from Seasons 1 and 2 and asked them to dream big to improve aging in America.  

In this episode, you’ll hear a wide range of ideas: from integrated child and eldercare to ballet training for young adults to walkable communities and many more. This ...

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November 26, 2024 29 mins

The holidays are a time for celebration, joy, and being with loved ones. Unfortunately, it can also be a time that brings stress and anxiety. Between travel, shopping, and managing family dynamics, this season can feel overwhelming. For caregivers and individuals with dementia, these challenges are often magnified. Travel and social gatherings can pose unique difficult...

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November 12, 2024 29 mins

Providing equitable aging research and care faces a major barrier: minorities that are disproportionately impacted by dementia are greatly underrepresented. Data shows that Black and African American individuals are twice as a likely to develop dementia. Hispanic and Latino populations are one and a half times as likely. At the core of this issue is what researchers call social and...

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October 29, 2024 27 mins

This November, millions of Americans will head to the polls for the 2024 presidential election. But while the right to vote is essential to our democracy, unfortunately, the process of voting can present unique challenges for individuals with disabilities like dementia, often requiring outside assistance. If you’re a caregiver, how much can you help someon...

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October 15, 2024 27 mins

An Alzheimer's doctor goes to the opera...This isn't the start of a bad joke; it's the result of a collaboration between the Penn Memory Center and leaders of Philadelphia's arts community. The first of its kind at PMC, the Arts on the Mind Festival explored the intersection of the mind and art over a two-month event span. Music, literature, visual art, and film were a...

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October 1, 2024 22 mins

Over the past two years, the world has seen major developments in Alzheimer’s disease treatment with the release of two new medications: Lecanamab, marketed as Leqembi, and Donanemab, marketed as Kisunla. These two treatments are the first of their kind to reduce the physical signs of Alzheimer’s disease in the brain and potentially slow down the progression of cognitive decline.

In the ...

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September 17, 2024 9 mins

The first four episodes mark the end of the first season of the Age of Aging. But don’t worry! The second season of the Age of Aging will resume two weeks from now. With a slightly different format, the stories of Season 2 will feature old and new voices from researchers, clinicians, and patients.   

 

In this episode, hosts Terrence and Jake ...

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September 3, 2024 41 mins

Diagnostic testing is at the heart of both the clinical care and research at the Penn Memory Center. Patients and research participants alike undergo various diagnostics such as PET scans, MRI scans, and cognitive tests. These tools help clinicians turn symptoms such as dementia into a diagnosis like Alzheimer’s disease. But what are these tests? And what can they actually tell us ...

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August 20, 2024 34 mins

We often think of Alzheimer’s disease and other causes of dementia in terms of their impact on the individual living with the disease. Of course, this is with good reason: a person with an age-related neurological disease will experience difficulties in their day-to-day life incomprehensible to most others. However, for every patient, there is one person or many people caring for t...

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August 6, 2024 42 mins

We all hope that we can age with as much independence, purpose, and well-being as possible in our later years. Unfortunately, aging is never so straightforward and we will all face our own unique challenges and complexities as we get older. So, with all this uncertainty, how do we get the most out of this later stage of life? 

 

In our second ...

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July 23, 2024 45 mins

Clinical advancements have made it easier than ever to learn your personal risk of developing age-related diseases such as Alzheimer’s. Through genetic testing or biomarker measurement, you can learn if you’re more likely than your peers to develop dementia as you age.

Do you want to know?

In our first episode of the Age of Aging, we explore exactly that question.

First, we’ll hear about...

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