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March 18, 2025 11 mins

On episode 46 of Inside the Studio, Dr. Joseph G. Rogers sits down with Dr. Mathew S. Maurer to explore cardiac amyloidosis, highlighting the importance of patient evaluation and diagnostic algorithms. They discuss the necessity of thorough diagnostic processes, including biopsies, and the significance of genotyping. 

Further in the discussion, they cover:

  • The practical approach to diagnosing cardiac amyloidosis from initial patient presentation.
  • The critical steps in differentiating AL and TTR amyloidosis.
  • The role of genotyping in determining prognosis and guiding treatment decisions.
  • The importance of endomyocardial biopsies, particularly when monoclonal proteins are identified.
  • Insights into the natural history of wild-type TTR amyloidosis and the factors influencing its development in older adults.
  • The latest therapeutic strategies and the necessity of multidisciplinary collaboration, particularly with hematology-oncology.

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