Epileptic Disorders Podcast: Weekly Digest

Disorders discussed:

- Maple syrup urine disease

- Phenylketonuria

Article reference:

Kapoor D, Sharma S, Kaminska A, Nabbout R, Chemaly N, Schiff M, De Lonlay P, Eisermann M. Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and...

Disorders discussed:

- Biotinidase deficiency (BTD) and

- Holocarboxylase synthetase (HCS) and

- Urea cycle disorders

Article reference:

Kapoor D, Sharma S, Kaminska A, Nabbout R, Chemaly N, Schiff M, De Lonlay P, Eisermann M. Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnos...

Disorders discussed: Disorders of amino acid metabolism and disorders involving sulfur-containing amino acid metabolism

- Glycine encephalopathy (nonketotic hyperglycemia)

- Serine biosynthesis disorders

- Molybdenum cofactor deficiency and sulfite oxidase deficiency 

Article reference:

Kapoor D, Sharma S, Kaminska A, Nabbout R, Chemaly N, Schiff M, De Lonlay P, Eisermann M. Seizures and electroencepha...

Disorders discussed:

- Pyridoxine-dependent developmental and epileptic encephalopathy (PD-DEE)

- Pyridoxamine-5’-phosphate oxidase (PNPO) deficiency DEE

- FOL1-related cerebral folate transport deficiency

Article reference:

Kapoor D, Sharma S, Kaminska A, Nabbout R, Chemaly N, Schiff M, De Lonlay P, Eisermann M. Seizures and electro...

Article reference:

Kapoor D, Sharma S, Kaminska A, Nabbout R, Chemaly N, Schiff M, De Lonlay P, Eisermann M. Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and review of the literature. Epileptic Disord. 2025 Oct;27(5):745-802.

https://onlinelibrary.wile...

Part 5 - SE in adults and children - Etiology and age

Article reference:

Leitinger M, Bosque-Varela P, Kuchukhidze G, Leitner U, Höfler J, Kalss G, Rossini F, Pilz G, Novak H, Mauritz M, Poppert K, Toma A, Trinka E. Seminars in epileptology: How to diagnose status epilepticus in adults and children. Epileptic Disord. 2025 Aug;27(4):530-549.

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Part 4 - SE in adults and children - EEG correlate of IIC, possible NCSE, and high risk patterns

Article reference:

Leitinger M, Bosque-Varela P, Kuchukhidze G, Leitner U, Höfler J, Kalss G, Rossini F, Pilz G, Novak H, Mauritz M, Poppert K, Toma A, Trinka E. Seminars in epileptology: How to diagnose status epilepticus in adults and children. Epileptic Disord. 2025 Aug;27(4):...

Part 3 - SE in adults and children - EEG correlate  of convulsive and non-convulsive SE

Article reference:

Leitinger M, Bosque-Varela P, Kuchukhidze G, Leitner U, Höfler J, Kalss G, Rossini F, Pilz G, Novak H, Mauritz M, Poppert K, Toma A, Trinka E. Seminars in epileptology: How to diagnose status epilepticus in adults and children. Epileptic Disord. 2025 Aug;27(4):530-549.

Part 2 - SE in adults and children - Semiology

Article reference:

Leitinger M, Bosque-Varela P, Kuchukhidze G, Leitner U, Höfler J, Kalss G, Rossini F, Pilz G, Novak H, Mauritz M, Poppert K, Toma A, Trinka E. Seminars in epileptology: How to diagnose status epilepticus in adults and children. Epileptic Disord. 2025 Aug;27(4):530-549.

https://on...

Part 1 - Status epilepticus (SE) in adults and children - Introduction

Article reference:

Leitinger M, Bosque-Varela P, Kuchukhidze G, Leitner U, Höfler J, Kalss G, Rossini F, Pilz G, Novak H, Mauritz M, Poppert K, Toma A, Trinka E. Seminars in epileptology: How to diagnose status epilepticus in adults and children. Epileptic Disord. 2025 Aug;27(4):530-549.

Part 8 - Seizure semiology - somatotopic modifiers, time-related features, conclusion

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/ep...

Part 7 - Seizure semiology - postictal phenomena

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430. Erratum in: Epileptic Di...

Part 6 - Seizure semiology - autonomic features

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430. Erratum in: Epileptic Dis...

Part 5 - Seizure semiology - affective and cognitive features

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430. Erratum in:...

Part 4 - Seizure semiology - sensory phenomena

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430. Erratum in: Epileptic Diso...

Part 3 - Seizure semiology - elementary and complex motor signs

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430. Erratum i...

Part 2 - Seizure semiology - consciousness, awareness, and responsiveness 

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430...

Part 1 - Seizure semiology - Introduction

Article reference:

Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disord. 2022 Jun 1;24(3):447-495. English. doi: 10.1684/epd.2022.1430. Erratum in: Epileptic Disord. 2...

Part 5 - Management of Post-stroke seizures

Article reference:

Zelano J, Holtkamp M, Agarwal N, Lattanzi S, Trinka E, Brigo F. How to diagnose and treat post-stroke seizures and epilepsy. Epileptic Disord. 2020 Jun 1;22(3):252-263. PMID: 32597766.

https://onlinelibrary.wiley.com/doi/10.1684/epd.2020.1159

Speaker: Ma...