Hope in the Pipeline

Welcome to the third part of our Hope in the Pipeline series on hypersomnolence disorders. In this episode, we dive deep into:

🔹 Medications used to treat narcolepsy – from older stimulants to newer, longer-lasting options

🔹 The role of antidepressants and sodium oxybate in managing symptoms like cataplexy

🔹 Key differences between narcolepsy and idiopathic hypersomnia (IH)

🔹 Current treatment options for IH and why diagnosis...

Welcome back to Hope in the Pipeline! In this episode, we continue our deep dive into narcolepsy, exploring: ✅ What causes cataplexy (sudden loss of muscle tone) ✅ How dream sleep paralysis can leak into wakefulness ✅ Vivid sleep-related hallucinations and automatic behaviors ✅ The detailed diagnostic process for narcolepsy, including sleep studies and genetic testing ✅ How narcolepsy impacts daily life, work, and education ✅ Impo...

Have you ever felt overwhelmingly sleepy even after a full night’s rest? Narcolepsy and idiopathic hypersomnia are two central disorders of hypersomnolence that affect millions worldwide — often undiagnosed.

In this episode of Hope in the Pipeline, we explore:

🧠 What narcolepsy and idiopathic hypersomnia are

🧠 Key symptoms and differences between the two

🧠 Causes, diagnosis, and treatment options

🧠 The role of the immune system...

Did you know that the number of blood pressure medications you take could be a sign of untreated obstructive sleep apnea?

There is a strong connection between obstructive sleep apnea (OSA) and hypertension, including the serious health risks of untreated OSA—from stroke and dementia to heart failure and even death. In this episode, Dr. Paul Wylie discusses a new clinical trial testing a promising medication designed to treat BOTH s...

Did you know that 12% of women experience chronic or episodic migraines, and for many, they’re tied to hormonal cycles? In this episode of Hope in the Pipeline, Dr. Paul Wylie dives into the causes, symptoms, and treatments of menstrual migraines.

🧠In this episode, you’ll learn:

What causes menstrual migraines (hint: estrogen & hormone changes)

How they differ from common migraines

Why they often respond poorly to current medi...

In this episode of Hope in the Pipeline, Dr. Paul Wylie dives deep into chronic insomnia disorder—what causes it, how it affects both children and adults, and the latest research aimed at treating it.

🧠 Learn about: The types of insomnia symptoms Differences in diagnosing pediatric vs. adult insomnia Behavioral vs. pharmacological treatments The real-life impact of chronic sleep disruption Two new clinical trials are now enrollin...

Attention Deficit Hyperactivity Disorder (ADHD) affects millions of children — but early diagnosis and the right treatment can make a world of difference. In this episode of Hope in the Pipeline, Dr. Paul Wylie, Neuropsychiatry and Sleep Medicine Specialist, explores the symptoms, causes, and treatment options for pediatric ADHD.

We also dive into an exciting new clinical research trial for children ages 4 to 5 years and 7 months, ...

In this episode of Hope in the Pipeline, Dr. Paul Wylie sheds light on narcolepsy—a complex neurological sleep disorder marked by overwhelming daytime sleepiness and sudden muscle weakness known as cataplexy. He breaks down the different types of narcolepsy, explores its symptoms, and dives into the science behind it, from genetic links to autoimmune triggers. The conversation also highlights current treatment options...

Millions of workers rely on shift work to keep essential services running, but at what cost? Dr. Paul Wylie, a Neuropsychiatry and Sleep Medicine Specialist, dives into Shift Work Sleep Disorder (SWSD)—its impact on sleep, productivity, and long-term health risks like mood disorders, diabetes, and even cancer.

Preferred Research Partners is currently enrolling participants for a 12-week clinical t...

This conversation explores the emerging field of psychedelic research in mental health, focusing on the potential of psychedelic medications to treat mood disorders. Dr. Paul Wylie, a neuropsychiatrist, discusses the historical context of mental health treatments, the evolution of psychedelics in therapy, and the mechanisms by which they may promote neuroplasticity and improve mental health outcomes. Katie Walker, a therapist and p...