The Orange Pill Podcast

In this episode, we explore a growing issue in nutraceutical clinical research: the misuse of predicted margins to gloss over incomplete data in virtual trials. When predictive models are used in place of raw results—without validation or transparency—scientific rigor is compromised. We break down what predicted margins are, when they should (and shouldn’t) be used, and how this impacts regulatory credibility.

In this episode, we discuss a new clinical trial conducted by KGK Science and published in the British Medical Journal of Nutrition, Prevention and Health. This randomised, double-blind, placebo-controlled study evaluated how supplementation with a fava bean protein supplement impacts human strength and endurance when combined with resistance training.

In this episode of the Orange Pill Podcast, we explore the growing trend of virtual clinical trials in the dietary supplement and conventional food industries. Learn how these innovative trial designs are making research more accessible, efficient, and data-driven. 

In this episode of The Orange Pill Podcast, we continue our deep dive into cognitive health, exploring the science behind brain supplements and how they support memory, focus, and overall mental clarity.

Tune in now for expert insights and practical takeaways!

In this episode, we dive into groundbreaking research on cognitive health, exploring a clinical study conducted at KGK Science on Neuriva, a leading brain health supplement. Learn how it impacts cognitive performance in healthy adults with self-perceived memory concerns—delivering insights you won’t want to miss!

Tune in for the science, and what it means for your brain health.

In this episode, we unravel the fascinating world of GLP-1 agonists—widely known for their role in diabetes and weight management—and their potential as functional food ingredients. From scientific breakthroughs to real-world applications and regulatory hurdles, this discussion offers a comprehensive look at what the future may hold for these powerful metabolic modulators.

Could plant-based protein be just as effective as whey for muscle growth? In this episode, we break down a clinical trial conducted by KGK Science for Roquette, comparing pea protein and whey protein head-to-head. We discuss the findings, what they mean for athletes and fitness enthusiasts, and whether plant-based proteins are ready to take over the supplement industry.

In Episode 5, we explore the science behind collagen supplements, including a KGK Science clinical trial on marine collagen from Vinh Wellness, published in the Journal of Cosmetic Dermatology. Tune in to discover what the research says about collagen’s impact on skin hydration, elasticity, and wrinkle reduction—and whether your supplement is really doing what it claims!

Many believe dietary supplements aren't regulated, but they are. This podcast's Part I explores the history of their regulation in the US, from the 1960s Vitamin and Mineral Regulations to the NLEA of 1990 for labeling and the 1994 Dietary Supplement Health and Education Act. Stay tuned for future episodes detailing this fascinating journey.