The Human 5.0 Project

The Human 5.0 Project

The Human 5.0 Project is the podcast where science meets self-optimization. Hosted by Ultimate Biohacker 10X, this show explores the real research, real data, and real dosing behind today’s most effective biohacking tools — from peptides, longevity molecules, and nootropics to recovery devices, lifestyle strategies, sleep optimization, training principles, and cutting-edge performance tech. Each episode breaks down complex biology into practical, actionable protocols you can use to improve energy, metabolism, cognition, and overall healthspan. No hype. No fluff. Just evidence-based insights for people who want to understand their bodies, upgrade their biology, and unlock their highest potential. If you’re ready to optimize your life one pathway at a time, you’re in the right place.

Episodes

December 8, 2025 10 mins

Are synthetic drugs silently overwhelming your body’s detox machinery? In this episode of The Human 5.0 Project, Ultimate Biohacker 10X breaks down the real difference between natural biological pathways and lab-created pharmaceuticals — and why your body reacts so differently to each one.

We dive deep into how the liver’s cytochrome P450 enzymes act as your internal garbage disposal system, processing hormones, toxins, plant compo...

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In this episode of The Human 5.0 Project, we dive deep into SLU-PP-332, a groundbreaking compound that promises to revolutionize metabolic health and longevity. Dosing in notes.

What You’ll Learn:
  • Origins and Development: Discover how SLU-PP-332 was developed at Saint Louis University and the brilliant minds behind it.

  • Mechanism of Action: Learn how this compound mimics exercise at the cellular level, boosting mitochondrial...

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In this episode of the Human 5.0 Project, we delve into the complex world of ALS (amyotrophic lateral sclerosis). We start with a brief overview of what ALS is, and then we explore the current standard treatments, including medications like Riluzole and Edaravone. The heart of the episode focuses on the innovative supportive therapies being used in the U.S.—from functional medicine and nutritional supplements to cutting-edge peptid...

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In this episode of The Human 5.0 Project, we unpack one of the most controversial molecules in modern medicine: nicotine. Not smoking. Not vaping. Nicotine itself.

For decades, nicotine has been labeled as “highly addictive” by the FDA and Surgeon General—but emerging research from the 1990s through 2025 paints a far more complex picture. We dive into:

🔬 What the science actually shows: 1990s–2025

• Big Tobacco documents revealing...

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Welcome back to The Human 5.0 Project! In today’s episode, we’re diving deep into Thymosin Alpha-1 (TA1)—the immune-modulating peptide that’s been quietly revolutionizing immune resilience for decades.

We cover:

  • The fascinating history of TA1: From its discovery in the 1970s to its role in 2025 as a trusted tool for biohackers and longevity enthusiasts.

  • How TA1 works: We break down how this 28-amino-acid peptide acts as the...

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In this 9-minute episode, we break down Semaglutide (Ozempic/Wegovy/Rybelsus) — the GLP-1 agonist that reshaped weight loss, longevity, and metabolic health. Even as newer peptides like Tirzepatide and Retatrutide enter the spotlight, Semaglutide remains a proven, reliable, and highly effective tool for weight management and healthspan optimization.

We cover everything you need to know: ✔️ What Semaglutide is & how it works ✔️ ...

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Welcome back to The Human 5.0 Project – where we upgrade the human operating system.

In today’s episode we go full-send on Retatrutide , Eli Lilly’s triple-agonist that just obliterated every weight-loss record in 2025: up to 24.2% body weight loss in 48 weeks (that’s 50–60+ lbs for most people) with simultaneous improvements in A1c, liver fat, blood pressure, and triglycerides. People are already calling it the “Ozempic killer” an...

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In this 5-minute deep dive, we unpack GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper), the copper-bound tripeptide that’s absolutely dominating 2025 longevity and aesthetic medicine conversations. Once a well-kept secret of high-end skincare, GHK-Cu is now the #1 most-researched regenerative peptide worldwide — and for good reason.

Here’s exactly what we cover:

  • Why natural GHK levels drop from ~200 ng/mL in your 20s to under 20 ng/...
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Dive into the world of Vilon, one of the original Khavinson peptides, in this focused seven-minute breakdown. We cover what it does (Lys-Glu dipeptide from thymus extracts), how it works (chromatin remodeling, gene upregulation), and the exact research dosing protocols used in cell cultures and rodents. If you're into longevity, immunosenescence, or peptide stacks, this episode unpacks the science behind restoring youthful immune f...

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In this episode, we dive into holistic approaches to managing Crohn’s disease and related inflammation. From peptides and supplements to diet and lifestyle tweaks, discover how you can create a balanced, integrative plan for symptom relief without relying solely on heavy-duty medications. Always discuss treatment plans with your healthcare provider.

 

#CrohnsDisease #Inflammation #HolisticHealth #Peptides #DietAndLifestyle #GutHeal...

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In this episode, we dive deep into the world of Ipamorelin, a powerful peptide known for boosting growth hormone levels, enhancing recovery, and supporting anti-aging. Whether you're curious about how it works, the benefits, or the potential drawbacks, we've got you covered in a quick seven-minute deep dive.

 

#Ipamorelin #Peptides #Biohacking #Longevity #HumanPerformance #Wellness #PodcastLife

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In this episode of The Human 5.0 Project, Ultimate Biohacker 10X breaks down MOTS-c — a mitochondrial peptide that’s making waves in the longevity and metabolic health communities. Learn how this small but mighty peptide works, why researchers are excited about its potential benefits for metabolism, insulin sensitivity, and healthy aging, and what current research says about dosing and safety. Remember, MOTS-c is still in the exper...

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BPC-157 is one of the most talked-about peptides in the biohacking, longevity, and performance science world — yet most people still don’t understand what it actually does or how it works. In this episode, I break down the real science behind BPC-157, separating hype from reality and giving you a clear understanding of its role in regeneration, recovery, and gut health.

We explore the origins of BPC-157, how it’s derived from a nat...

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November 30, 2025 14 mins

The KLOW Peptide has become one of the most talked-about compounds in the optimization and performance world — but most people still have no idea what it actually does or how it fits into the KLOW framework. In this episode, I break down the science behind the KLOW Peptide, how it works, the pathways it influences, and why it’s gaining so much attention in the biohacking community.

You’ll learn how the KLOW Peptide interacts with t...

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