Peptalk: Peptides Unpacked

One in eight adults report feeling exhausted almost every day for months at a time — and for women 18-44, it's closer to one in five. That's the jumping-off point for this episode, where Dr. Kylie Burton and Jessica Brickie tackle a molecule that shows up on nearly every peptide company's menu, even though it isn't technically a peptide at all: NAD+.

The hosts break down what NAD+ actually is (a dinucleotide, not a peptide), w...

Interested in the Business of Peptides? This episode is for you.

Peptides keep getting louder online, but the business side is where people get confused fast, especially when safety, regulations, and “gray market” sourcing are in the mix. We’re sharing a gold-level recording from a live call where we get specific about how a legitimate telehealth peptide company works, what “referral” really means, and ...

Your gut doesn’t know the difference between a peptide and a piece of chicken breast, and that one sentence changes how you should think about “oral peptides” forever. 

We’re Kylie Burton and Jessica Briecke, and we’re unpacking what actually happens when a peptide hits stomach acid, digestive enzymes, and then the small intestine. If you’ve ever wondered why a capsule, powder, or drink mix c...

This is a business episode, not a science one — and it starts with a woman most people only know for a pink Cadillac. Dr. Kylie Burton and Jessica Brickie tell the story of Mary Kay Ash: 25 years in corporate sales, passed over for a promotion in favor of a man she'd personally trained, and once awarded a fisherman's flashlight as a prize for being one of the company's top performers. At 45, newly widowed just a month before ...

In early July, the FDA held a major hearing near Washington, DC, addressing the regulatory status of a group of compounded peptides — and Jessica was there. In this episode, Dr. Kylie Burton and Jessica Briecke break down what actually happened at the hearing (as opposed to the wave of secondhand opinions that circulated online afterward). 

And shocker, we were the ONLY company who showed up! And we showed up in full forc...

Sexual wellness and libido are often treated as taboo topics — something couples quietly struggle with instead of talking about, and often something one partner mistakenly internalizes as their own fault. In this episode, Dr. Kylie Burton and Jessica Brickie sit down with returning guest Jennifer Wersland for an unusually candid conversation about desire, connection, and what actually helped her and her husband rebuild intima...

Why do so many patients — not just those with endometriosis — end up cycling through specialists, labs, and prescriptions without ever getting a real answer? In this episode, Dr. Kylie Burton and Jessica Brickie sit down with gynecologist and women's health advocate Dr. Joelle Osias to make the case for a different model of medicine altogether: one built on root causes, individualized labs, and tools like peptides and G...

Sermorelin has a half-life of just 10 to 12 minutes — so how does something that leaves your system that fast do anything at all? That's the question Dr. Kylie Burton and Jessica Brickie open with in this episode, using it as the jumping-off point for a side-by-side look at two related growth hormone peptides: sermorelin and tesamorelin.

The hosts explain sermorelin's core mechanism — a "gentle nudge" to the pituitary gl...

Callie Isley is 36, lives in Texas, and spent five years trying to become a mother — multiple fertility evaluations, IUIs, and a looming $25,000 IVF bill — before her story took an unexpected turn. In this deeply personal episode, Dr. Kylie Burton and Jessica Brickie sit down with Callie to talk through the emotional weight of infertility, the lifestyle changes that came before her pregnancy, and the surprise that chang...

The peptide world is full of hype, half-truths, and confusing acronyms, so we’re slowing down and getting specific about two names that keep showing up: BPC-157 and TB-500. 

Ready to understand BPC-157 (Body Protection Compound) in plain English and why its headline is tissue repair? Next up is the peptide it's often combined with: TB-500, a thymosin beta 4 fragment. It works with actin inside your cells, helping ...

Why do GLP-1 peptides keep showing up in places like heart health, kidney function, inflammation, sleep apnea, joint pain, cravings, and even long-range conversations about aging? Yet, most people believe they only have a positive impact on weight loss. 

If you believe GLP-1s are only good for weight loss, think again. 

We make the science simple without dumbing it down: 

• We explain randomized controlled tri...

Why are we talking about Hormone Replacement Therapy on a Peptide Podcast? Well, peptides and hormones go great together and now, you have access to BOTH with our telemedicine company. 

The topic is needed too. 80% of women show up to a menopause-related doctor visit and walk out with no treatment. Not “no hormones” no treatment at all. 

That stat frames a bigger problem we see every day: when you say “I d...

What if you didn't need a certification, a finished weight loss journey, or even a full understanding of peptides to build a thriving business around them? Tanya from Sydney, Montana is proof that all you really need is a source, a system, and the willingness to show up.

In this bonus business episode, Dr. Kylie Burton and Jessica Briecke sit down with Tanya Candy, RN, whose peptide business journey started with a cold DM she almost...

Ready to make money when you leave the office? This isn't just a dream for Jessica anymore. It's reality. 

Peptides get talked about like a trend, but what we really want is lasting change: more energy, more options, and a life that isn’t chained to the clock. We open with a simple idea that hits hard, we don’t work only to pay bills. We work to build dreams, and today Jess shares what it feels like when a decades-l...

The internet loves a scary headline, and “peptides placed in category two” might be the most misunderstood one yet. We’re Dr. Kylie Burton and Jessica Briecke, and we’re slowing the noise down to explain what’s actually happening with the FDA’s July 23–24 hearing and why it directly affects patient access to compounded peptides.

It started back in 2023 when compounding pharmacies pus...

A teratoma on her ovary. Then Hashimoto's. Then breast cancer. When it rains, it pours — and for Jen Gifford Wersland, it absolutely did.

In this episode, Dr. Kylie Burton and Jessica Briecke sit down with Jen, a breast cancer survivor whose story is equal parts harrowing and hopeful. From being dismissed in the ER with an IBS diagnosis (while carrying a peach-sized ovarian tumor) to navigating 12 rounds of chemo, a mastectomy...

What if the migraines you've managed your entire life weren't just about triggers — but about what your body was never making in the first place?

In this episode, Dr. Kylie Burton and Jessica Briecke sit down with Amy Cassles, a health-conscious, fitness-minded woman who spent 35 years doing everything right — and still couldn't outrun her migraines. From blood pressure meds and anti-seizure drugs in her teens and 20s, t...

Everyone wants glowing skin. But what if the serum, the cream, and the collagen powder aren't the problem — and neither is your skincare routine?

In this episode, Dr. Kylie Burton and Jessica Briecke sit down with Jen Gifford Wersland and Tanya Candy, RN, two women from Montana who stumbled onto a peptide-powered skincare approach that's turning heads — literally. People started stopping them to ask what they were doing ...

The “Barbie peptide” might be the most misleading nickname in wellness. We’re talking about Melanotan-2 and yes, it can deepen pigmentation, but the real conversation is about skin biology, UV protection, and what it means to make a decision without robust long-term human data. 

We kick off this episode with a relatable reality for redheads (like Dr. Kylie) and other fair-skinned listeners: 

• burning fa...