MedEvidence! Truth Behind the Data
Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com
Episodes
Proteus was a Greek sea god who could change his form, much like obesity is able to in the body. Doctors Michael Koren, Victoria Helow, and Michael Bernhardt come together in front of a live audience for a discussion on the myriad effects obesity has in and on the body. The doctors move through how excess weight affects the heart, skin, inflammatory systems, and more. They also explain that even when obesity doesn&apo...
Dr. Michael Koren is joined by Dr. Ezekiel "Zeke" Emanuel, an oncologist, bioethicist, and former White House advisor. Dr. Emanuel talks about his enduring interest in bioethics and the importance of ethics in areas like clinical research. The two doctors also talk about shared experiences at Harvard Medical School and Dr. Emanuel's contributions to bioethics in healthcare and research over his career. ...
Dr. Michael Koren joins Kevin Geddings to wax nostalgic about the past generation and what has changed for the better and for the worse. They note that there have been improvements in areas like food, but that air travel and the healthcare experience have deteriorated precipitously. They then contrast this with the massive improvements in the clinical research experience, where around 97-99% of participants say they w...
Radiologist Sue Jane Grosso-Rivas, MD joins cardiologist and clinical researcher Michael J. Koren, MD for Part Two of her Master's Series on breast imaging.
Dr. Grosso-Rivas talks about some of the complications that can occur during imaging, including dense breasts and their surprising prevalence. She also talks about new technologies in the imaging world, including contrast mammography and the use of AI in cance...
Dr. Michael Koren joins Kevin Geddings to explain how having a conversation with a medical professional who is tuned into your personal situation can help you understand the confusing and sometimes counterintuitive world of medical information. Cardiologist Dr. Koren uses the examples of coronary calcium scores and total cholesterol levels, which must be interpreted in the context of individual factors, such as age an...
Dr. Michael Koren Joins Kevin Geddings to discuss how the current political situation in Washington, D.C. is interfering with clinical research. They discuss the Vaxart trial, that is looking at the next generation of oral COVID vaccines, and how it has been affected by the Trump administration's inconsistent orders regarding vaccines. Dr. Koren points out that the Vaxart trial doesn't actually use mRNA and ...
Radiologist Sue Jane Grosso-Rivas, MD joins cardiologist and clinical researcher Michael J. Koren, MD to share her inspiring journey from aspiring secretary to Medical Co-Director of Breast Imaging at Summit Health. The doctoral duo discuss how Dr. Grosso-Rivas’s career was shaped by a school counselor who recognized her potential and encouraged her ambition.
Dr. Grosso-Rivas explains the fundamentals of breast mammogr...
Dermatologist Dr. Kristen Stewart digs deep to get to the root of psoriasis, a skin condition that affects approximately 3% of Americans. She talks about the role of systemic inflammation and how excessive inflammation can impact multiple body systems beyond just the skin. Dr. Stewart reviews her experience treating psoriasis, differentiating it from eczema, and the improvements in modern treatments. Dr. Stewart expla...
The back-to-school season represents an ideal time to reset health priorities and schedules, potentially more impactful than New Year's resolutions. Dr. Michael Koren joins Kevin Geddings to discuss how the changes that come with a new school year also include health changes and the inevitable spread of the flu. They talk about how new initiatives like BARDA, sponsored by the US Department of Health and Human Ser...
Cardiothoracic surgeon Dr. Mustafa "Dr. Kurk" Kurkluoglu joins cardiologist Dr. Michael Koren to discuss three mechanisms that affect heart health:
- Oxidative stress, dangerous charged particles that can damage cells
- Inflammation, an immune process that can get out of control
- Endothelial dysfunction, cells that line blood vessels stop working properly
The two doctors discuss what can be done to address s...
Cardiologist Dr. Michael Koren joins Kevin Geddings to talk about how we can learn a lot about medicine by knowing our history. The duo discuss how the history of healthcare, including smallpox inoculation in the 1800s, can inform us of the benefits of life-saving medicines like vaccines. They also talk about the history of obesity, the old city of St. Augustine, and how this all relates to modern medicine.
Dr. Michael Greger joins Dr. Michael Koren to discuss his life's work spreading nutritional knowledge. Dr. Greger talks about how a change in diet and lifestyle helped add 31 years to his grandmother's prognosis and how this event convinced him to go into medicine. He explains how a healthy diet is more about adding healthy foods than removing unhealthy foods and that eating is a zero-sum game. Dr. Greger sh...
Dr. Michael Koren joins Kevin Geddings to discuss how clinical research sites like ENCORE Research Group and medical information companies like MedEvidence can build and give back to communities by sharing what they know. Dr. Koren explains that medical experts can help people understand complex topics such as obesity and the skin condition hidradenitis suppurativa (HS) and help wash away some of the misinformation su...
Polycystic kidney disease (PKD) is the most common inherited kidney disease. Those with PKD have a 50% chance of passing it on to their children and have progressively worse kidney function as they age. World-known PKD researcher Dr. Fouad Chebib joins Dr. Michael Koren to discuss the symptoms, risks, genetic cause, and treatment options for PKD. They also get into some new treatment methods being explored in clinical...
Over the past 100 years, the poorest Americans have shifted from being underweight to becoming the group most likely to be overweight. Dr. Michael Koren joins Kevin Geddings to explore some of the social determinants of health underlying this trend. They touch on the complex biological, economic, and environmental factors contributing to higher obesity rates among economically disadvantaged Americans.
Dr. Michael Koren sits down with Dr. Allan Rosenfeld, a Canadian physician specializing in occupational medicine. The two doctors explore some of the realities of Canadian healthcare by moving through Dr. Rosenfeld's career in family practice, occupational medicine, and his personal use of the healthcare system. Dr. Rosenfeld offers candid insights that challenge common perceptions by discussing wait times, physi...
Dr. Michael Koren joins Kevin Geddings to introduce the concept of "scienceploitation." He explains that many marketing tactics in the health and supplement industry are disguised as scientific claims. For example, phrases like "supports immune health" often sound convincing but are meaningless without specific, evidence-based backing from rigorous clinical trials. Dr. Koren also highlights the ben...
Dr. Michael Koren hosts Brian Achille, the Chief Operating Officer of the Certified Clinical Research Professionals Society (CCRPS). Brian draws a distinction between doing clinical research casually and doing it professionally. The distinction highlights how professional training and attitudes prove to be a benefit to research and the community at large. The duo discuss how CCRPS offers training for many different cl...
Cardiologist Michael Koren joins Kevin Geddings to discuss how kidney disease can offect other body systems, including the heart. The doctor explains that people with kidney dysfunction have significantly higher risks for cardiovascular problems including heart attacks, heart failure, and strokes. Dr. Koren differentiates between typical, insurance-driven care and the attentive clinical research experience, noting tha...
Surveys show that 97-99% of participants who participate in one clinical research study would sign up for another. We wind out why in this episode, recorded in front of a live audience. Dr. Michael Koren and Nalini Jones, CCRC are joined by three clinical research patients to review the good, the bad, and the ugly in the history of clinical research. They also discuss the ins and outs of how the clinical research proc...
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